Results 141 to 150 of about 134,678 (321)

Pasteurellosis in laboratory rabbits: characterization of lipopolysaccharides of Pasteurella multocida by polyacrylamide gel electrophoresis, immunoblot techniques, and enzyme-linked immunosorbent assay [PDF]

, 1986
P J Manning, M A Naasz, D M DeLong, Susan L. Leary   +3 more
openalex   +1 more source

Human Microsporidial Infections [PDF]

, 2006
Microsporidia are eukaryotic, spore forming obligate intracellular parasites, first recognised over 100 years ago. Microsporidia are becoming increasingly recognised as infectious pathogens causing intestinal and extra-intestinal diseases in both immuno ...
D D, Duhlinska, G I, Anyanwu, I CJ, Omalu, P U, Inyama, V A, Pam   +4 more
core  

Unveiling Salt Tolerance Mechanisms in Plants: Integrating the KANMB Machine Learning Model With Metabolomic and Transcriptomic Analysis

Advanced Science, EarlyView.
Salt stress endangers coastal cereal crops, requiring resilient crop solutions. This study employs machine learning (KANMB) to analyze multi‐omics data from halophyte Spartina alterniflora, revealing 226 salt‐stress biomarkers and linking them to tolerance pathways. The MYB gene SaMYB35 regulates flavonoid biosynthesis under salinity.
Shoukun Chen, Hao Zhang, Shuqiang Gao, Kunhui He, Tingxi Yu, Shang Gao, Jiankang Wang, Huihui Li   +7 more
wiley   +1 more source

Microtiter enzyme-linked immunosorbent assay for immunoglobulin G cholera antitoxin in humans: method and correlation with rabbit skin vascular permeability factor technique [PDF]

, 1980
Charles R. Young, Myron M. Levine, John P. Craig, Roy M. Robins‐Browne   +3 more
openalex   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source

An overview of ELISA: a review and update on best laboratory practices for quantifying peptides and proteins in biological fluids

Journal of International Medical Research
The enzyme-linked immunosorbent assay (ELISA) detects antigen-antibody interactions by using enzyme-labelled conjugates and enzyme substrates that generate colour changes.
Suleyman Aydin, Elif Emre, Kader Ugur, Mustafa Ata Aydin, İbrahim Sahin, Vedat Cinar, Taner Akbulut   +6 more
doaj   +1 more source

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

Advanced Science, EarlyView.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang, Lin Tang, Yusi Wang, Xuejing Zhou, Zhenyu Ding, Li Yang   +5 more
wiley   +1 more source

Locoregional Immune Checkpoint Blockade and Remodeling of Lymph Nodes by Engineered Dendritic Cell‐Derived Exosomes for Suppressing Tumor Progression and Metastasis

Advanced Science, EarlyView.
The study develops engineered exosomes (EmDEX@GA) for locoregional immunomodulation of tumor‐draining lymph node (TDLN). EmDEX@GA can actively target to TDLN and remodel its immunosuppressive microenvironment through the synergistic effects of PD‐1/PD‐L1 blockade and STING pathway activation, subsequently enhance anti‐tumor immunity and suppress tumor ...
Yizhen Wang, Xiaomin Guo, Jingya Qin, Yifan Xue, Peng Zhang, Yadong Liu, Moyang Chen, Guanghao Zhu, Xinqiu Song, Lili Cheng, Bo Liu, Jie Liu, Jie Ren   +12 more
wiley   +1 more source

Early diagnosis of leptospirosis by conventional methods: One-year prospective study

Indian Journal of Pathology and Microbiology, 2008
Several techniques are available for the diagnosis of leptospirosis and microscopic agglutination test is considered as gold standard, but these require sophisticated techniques and instruments.
Sharma Krishna, Kalawat Usha
doaj  

An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma, Jie Wang, Min Jiang, Juanhua He, Fangyang Li, Dan Lu, Chao Su, Yan Chai, Wenjing Jin, Yu Chen, Catherine W.H. Zhang, Xiaopeng Ma, Hui Tan, George F. Gao, Shuguang Tan   +14 more
wiley   +1 more source