Results 151 to 160 of about 556,132 (392)

The University of Pittsburgh: a three and three-quarter-year experience with cadaveric renal transplantation under the point system. [PDF]

, 1989
Eight hundred and sixty kidney transplants were performed at the University of Pittsburgh over a 3.75-year period between January 1, 1986 and October 19, 1989.
Fung, JJ, Hakala, TR, Hickey, D, Iwaki, Y, Jordan, ML, Shapiro, R, Starzl, TE, Tzakis, AG   +7 more
core  

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Immunosuppression in stem cell clinical trials of neural and retinal cell types: A systematic review.

PLoS ONE
BackgroundPharmacologic immunosuppression regimes are commonly employed in stem cell clinical trials to mitigate host immune rejection and promote survival and viability of transplanted cells.
Shravan Gowrishankar, Matthew E Smith, Nathan Creber, Jameel Muzaffar, Daniele Borsetto   +4 more
doaj   +1 more source

Pediatric liver transplantation in 808 consecutive children: 20-Years experience from a single center [PDF]

, 2002
Fung, JJ, Jain, A, Kashyap, R, Kosmach-Park, B, Mazariegos, G, Reyes, J, Starzl, TE   +6 more
core   +1 more source

Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia

New England Journal of Medicine, 2022
R. Peffault de Latour, A. Kulasekararaj, S. Iacobelli, Sofie Terwel, Riley Cook, M. Griffin, C. Halkes, C. Récher, F. Barraco, E. Forcade, J. Vallejo, B. Drexler, J. Mear, Alexander Smith, E. Angelucci, R. Raymakers, M. D. de Groot, É. Daguindau, E. Nur, W. Barcellini, N. Russell, L. Terriou, A. Iori, Ursula La Rocca, A. Sureda, I. Sánchez-Ortega, B. Xicoy, I. Jarque, J. Cavenagh, F. Sicre de Fontbrune, S. Marotta, T. Munir, J. Tjon, S. Tavitian, A. Praire, L. Clément, Florence Rabian, L. Marano, A. Hill, E. Palmisani, P. Muus, F. Cacace, Camilla Frieri, M. V. van Lint, J. Passweg, J. Marsh, G. Socié, G. Mufti, C. Dufour, A. Risitano   +49 more
semanticscholar   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

Immunosuppression associated with the development of chronic infections with Rickettsia tsutsugamushi: adherent suppressor cell activity and macrophage activation [PDF]

, 1985
Thomas R. Jerrells
openalex   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Regulation of soluble CD127 protein release and corresponding transcripts expression in T lymphocytes from septic shock patients

Intensive Care Medicine Experimental, 2019
Julie Mouillaux, Camille Allam, Thomas Rimmelé, Thomas Uberti, Benjamin Delwarde, Julien Textoris, Guillaume Monneret, Estelle Peronnet, Fabienne Venet   +8 more
doaj   +1 more source