Results 271 to 280 of about 458,490 (361)

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, EarlyView.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

Immune-mediated necrotising myopathy following semaglutide treatment: a contributing factor? [PDF]

BMJ Case Rep
Lam B, Tiniakou E, Zhang XR, Assassi S.
europepmc   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Multidisciplinary management of thyroid eye disease (TED) in patients with latent tuberculosis or chronic hepatitis B. [PDF]

Thyroid Res
Vekinis JS, Lee J, Lee V, Aziz A, Jain R, Feeney C, Bravis V.   +6 more
europepmc   +1 more source

Liver transplantation of American veterans under FK 506 immunosuppression: A preliminary report [PDF]

, 1991
Fung, JJ, Gordon, RD, McCauley, J, Mieles, LA, Singh, N, Starzl, TE, Todo, S, Yokoyama, I   +7 more
core  

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Late-Onset Adenovirus-Induced Achalasia in a Kidney Transplant Recipient: A Case Report. [PDF]

Am J Case Rep
Alshaqaq AH, Elrggal ME, Aljawad MS, Ahmed MA, Amir AA, Alkhunaizi AM.   +5 more
europepmc   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Kaposi sarcoma in solid organ transplant recipients: updates in epidemiology, diagnosis, treatment and prevention. [PDF]

Front Immunol
Mularoni A, Cona A, Piazza C, Pecoraro F, Barozzi P, Luppi M.   +5 more
europepmc   +1 more source