Results 161 to 170 of about 269,737 (365)

Reactivation of hepatitis B virus associated with immunosuppression therapy. [PDF]

CMAJ, 2018
Lee JGH, Carruthers M, Ko HH.
europepmc   +1 more source

QUADRUPLE IMMUNOSUPPRESSION THERAPY USING A LOW DOSE COMBINATION REGIMEN OF RAPAMUNE (Rapa), CYCLOSPORINE (CsA), MYCOPHENOLATE MOFETIL (MMF), AND PREDNISONE IN MISMATCHED LRD AND LUD TRANSPLANTS

, 2004
Raja B. Khauli, Rabii Madi, Y. Hout, Walid Medawar, Maher Hussein, A Habbal, Majida Daouk, Marwan Uwaydah, Alexander M. Abdelnoor   +8 more
openalex   +1 more source

Cell Therapy for Parkinson’s Disease: A Translational Approach to Assess the Role of Local and Systemic Immunosuppression [PDF]

, 2016
Romina Aron Badin, Marta Vadori, Bernard Vanhove, Véronique Nerrière‐Daguin, Philippe Naveilhan, Isabelle Neveu, C. Jan, Xavier Lévêque, Éric Venturi, Pascal Mermillod, Nadja Van Camp, Frédéric Dollé, Martine Guillermier, Luca Denaro, Renzo Manara, Valentina Citton, Paolo Simioni, Paolo Zampieri, Domenico D’Avella, Domenico Rubello, F Fante, M Boldrin, Giulia Maria De Benedictis, Laura Cavicchioli, Dino Sgarabotto, Mario Plebani, Annalisa Stefani, P. Brachet, Gilles Blancho, Jean‐Paul Soulillou, Philippe Hantraye, Emanuele Cozzi   +31 more
openalex   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

MAINTENANCE THERAPY FOR IMMUNOSUPPRESSION WITH TACROLIMUS AND MYCOPHENOLATE MOFETIL WITHOUT STEROID.

, 2004
N Ogawa, H Asano, K. Takahashi, Tetsuya Torii, Y Toshimitu, Masaaki Miyazawa, Nozomi Shinozuka, Isamu Koyama   +7 more
openalex   +1 more source

Vernal keratoconjunctivitis: culmination of management using immunosuppression, surgical and prosthetic therapy over quarter century [PDF]

, 2016
Shilpa Das, Anand Pasari, Veena Sangwan
openalex   +1 more source

Role of Tunneling Nanotubes in Arachidonic Acid Transfer and Macrophage Function Reprogramming in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
Tunneling nanotubes facilitate the transfer of long‐chain fatty acids, primarily arachidonic acid, from tumor cells to macrophages, leading to lipid accumulation and activation of the PI3K‐Akt pathway. This drives a shift from the anti‐tumor CD5L⁺ phenotype to a pro‐tumor TREM2⁺ phenotype.
Meiru Chen, Shangyumeng Zhao, Xiaoli Xie, Jiaqi Wang, Miao Su, Lixian Zhang, Ruolin Cui, Dongqiang Zhao   +7 more
wiley   +1 more source

Center-driven and Clinically Driven Variation in US Liver Transplant Maintenance Immunosuppression Therapy: A National Practice Patterns Analysis. [PDF]

Transplant Direct, 2018
Nazzal M, Lentine KL, Naik AS, Ouseph R, Schnitzler MA, Zhang Z, Randall H, Dharnidharka VR, Segev DL, Kasiske BL, Hess GP, Alhamad T, McAdams-Demarco M, Axelrod DA.   +13 more
europepmc   +1 more source

Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden [PDF]

, 2017
Meredith L. Stone, Katherine B. Chiappinelli, Huili Li, Lauren Murphy, Meghan Travers, Michael J. Topper, Dimitrios Mathios, Michael Lim, Ie‐Ming Shih, Tian‐Li Wang, Chien‐Fu Hung, Vipul Bhargava, Karla R. Wiehagen, Glenn S. Cowley, Kurtis E. Bachman, Reiner Strick, Pamela L. Strissel, Stephen B. Baylin, Cynthia A. Zahnow   +18 more
openalex   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source