Results 201 to 210 of about 269,737 (365)

Successful recovery from severe COVID‐19 pneumonia after kidney transplantation: The interplay between immunosuppression and novel therapy including tocilizumab

, 2020
Andrea Lauterio, M. Valsecchi, S Santambrogio, Riccardo De Carlis, Marco Merli, Angelo Calini, Leonardo Centonze, Vincenzo Buscemi, Maurizio Bottiroli, Massimo Puoti, Roberto Fumagalli, Luciano De Carlis   +11 more
openalex   +1 more source

Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis

Advanced Science, EarlyView.
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan, Han Ma, Jespar Chen, Gaifeng Ma, Alok Jha, Sipin Tan, Yaxi Zhu, Meidong Liu, Ke Liu, Xianzhong Xiao, Monowar Aziz, Huan Chen, Ping Wang, Huali Zhang   +13 more
wiley   +1 more source

Tacrolimus in solid organ transplantation [PDF]

, 1996
Fung, JJ, Starzl, TE, Todo, S
core  

Performance of World Health Organization (WHO) Immunological Response to Predict Virological Failure in Patients With Severe Versus Moderate Immunosuppression at Antiretroviral Therapy Initiation

, 2015
Martin Herbas Ekat, Merlin Diafouka, P Nzounza   +2 more
openalex   +1 more source

CARDIAC PET GUIDED IMMUNOSUPPRESSION THERAPY IN THE TREATMENT OF CARDIAC SARCOIDOSIS

, 2020
Clark Yarber, Mark I. Travin, Peter Vlismas, Omar Saeed, Sandhya Murthy, Patricia Chavez, S. Vukelic, Snehal R. Patel, J. Shin, Ulrich P. Jorde, Daniel B. Sims   +10 more
openalex   +1 more source

Abnormal β‐Hydroxybutyrylation Modification of ARG1 Drives Reprogramming of Arginine Metabolism to Promote the Progression of Colorectal Cancer

Advanced Science, EarlyView.
Alterations in arginine metabolism and β‐hydroxybutyrylation (Kbhb) modifications play a critical role in tumor progression. This study reveals valuable insights into arginine metabolism reprogramming involving the ARG1‐Kbhb/P300/SLC3A2 signaling axis and uncovers an effective therapy combining BHB with ARG1 inhibitor through conventional enzymatic and
Chuman Lin, Zhiyang Li, Xiaotong Zhu, Wanbing Zhou, Xiansheng Lu, Jiali Zheng, Jie Lin   +6 more
wiley   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

FK506 IN CLINICAL ORGAN-TRANSPLANTATION [PDF]

, 1991
ABUELMAGD, K, ARMITAGE, J, BRONSTER, O, FUNG, JJ, GORDON, R, JAIN, A, JORDAN, M, KORMOS, R, MARTIN, M, SELBY, R, SHAPIRO, R, STARZL, TE, STIEBER, A, TODO, S, TZAKIS, A   +14 more
core  

The Development of Clinical Renal Transplantation [PDF]

, 1990
Ackerman, Belzer, Billingham, Borel, Brown, Burnet, Calne, Calne, Calne, Calne, Carpenter, Collins, Cosimi, Dempster, Dubost, Elkinton, Ferguson, Groth, Hamburger, Hau, Hume, Hume, Jaboulay, Jamieson, Kahan, Kahan, Kino, Kissmeyer-Nielsen, Kohler, Kuss, Lawler, Lindsley, Medawar, Merrill, Merrill, Michon, Murray, Murray, Murray, Murray, Murray, Pierce, Reemtsma, Schwartz, Servelle, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Sweny, Terasaki, Terasaki, Thomas E. Starzl, Ting, Todo, Unger, Voronoy, Williams, Woodruff, Zukoski   +71 more
core   +1 more source

Cryogel‐Based Dendritic Cell Immunotherapy for Post‐Surgical Breast Cancer Treatment

Advanced Science, EarlyView.
A multifunctional GelMA cryogel enables dendritic cell immunotherapy that synergizes with doxorubicin and PD‐1 blockade, driving robust post‐surgical T‐cell immunity and suppressing TNBC recurrence. Abstract Triple‐negative breast cancer (TNBC) is an aggressive malignancy with high mortality and limited treatment options.
Lam‐Duc‐Huy Nguyen, Sheng‐Liang Cheng, Yu‐Ting Yen, Hsin‐Mei Lee, Te‐Haw Wu, Jane Wang, Shu‐Yi Lin, Yunching Chen   +7 more
wiley   +1 more source