Results 221 to 230 of about 269,737 (365)

Frequent achievement of a drug-free state after orthotopic liver transplantation [PDF]

, 1993
Abu-Elmagd, K, Demetris, AJ, Fung, JJ, Nalesnik, M, Nour, B, Ramos, H, Reyes, J, Starzl, TE, Todo, S, Trucco, M, Tzakis, A, Zeevi, A   +11 more
core  

Genital Dysplasia and Immunosuppression: Why Organ-Specific Therapy Is Important

, 2019
Raphael Sager, Pascal Frei, Urs C. Steiner, Daniel Fink, Cornelia Betschart   +4 more
openalex   +1 more source

Nanosensitizer for Cancer Radioimmunotherapy via Anti‐IL‐35 Blockade Boosted Innate Immunity Activation

Advanced Science, EarlyView.
Zheng et al. designed a tumor microenvironment (TME)‐responsive nanosystem, HmBMH@MSA‐2. It targets tumors, releases MSA‐2 and Mn ions in high glutathione (GSH) conditions, achieving STING agonist delivery and MRI. The nanosystem promotes chemodynamic therapy (CDT), achieves radiosensitization, and activates the cGAS‐STING pathway.
Yinfei Zheng, Shuting Zheng, Yushu Liao, Zede Wu, Chenxi He, Qiuyu Li, Honglei Hu, Zheyu Shen, Yikai Xu, Chenggong Yan, Bingxia Zhao, Meirong Hou   +11 more
wiley   +1 more source

Immunosuppressant management in palliative care: a systematic review. [PDF]

BMC Palliat Care
Birchler KM, Hertler C, Pfrunder T, Blum D, Schettle M.   +4 more
europepmc   +1 more source

Glabridin‐Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity

Advanced Science, EarlyView.
Complex 6d could promote tumor immunogenicity by targeting thioredoxin reductase (TrxR) and remodel immunosuppressive microenvironment by the mitogen‐activated protein kinase (MAPK) pathway inhibition simultaneously. This study provides a novel approach to develop metal immunomodulatory agents by designing gold complexes incorporating natural products,
Zhaoran Wang, Meiyu Wang, Qiong Chen, Mengshi Wang, Fuwei Li, Lin Lv, Zhenfan Wen, Zhongren Xu, Yixia Yang, Chunyang Bi, Wukun Liu   +10 more
wiley   +1 more source

Fibrillary glomerulonephritis disease natural history and outcomes: a retrospective two centre cohort study. [PDF]

BMC Nephrol
Zhang Y, Baharani J, Ajayi B, Pinney J.
europepmc   +1 more source

Contribution of organ transplantation to the biology of cancer [PDF]

, 1990
Starzl, TE
core  

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

Advanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang, Xiao‐Mei Zhang, Xi Wu, Cheng‐Kai Zhou, Zhen‐Zhen Liu, Xue‐Yue Luo, Liang Zhang, Wei Chen, Yong‐Jun Yang   +8 more
wiley   +1 more source

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

Regulatory T Cell in Kidney Transplant: The Future of Cell Therapy? [PDF]

Antibodies (Basel)
Matarneh A, Patel M, Parikh K, Karasinski A, Kaur G, Shah V, Ghahramani N, Trivedi N.   +7 more
europepmc   +1 more source