Results 251 to 260 of about 290,024 (350)

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

The Role of mTOR Inhibitors in COVID-19 Outcomes Among Heart Transplant Recipients. [PDF]

open access: yesViruses
Kuczaj A   +8 more
europepmc   +1 more source

Cyclosporin A and steroids for liver and heart transplantation [PDF]

open access: yes, 1982
Bahnson, HB   +8 more
core  

Supplementary Figure 7 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma

open access: gold
Gwendolyn M. Cramer   +18 more
openalex   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu   +15 more
wiley   +1 more source

Weaning of immunosuppression in long-term recipients of living related renal transplants: A preliminary study [PDF]

open access: yes, 1995
Fung, JJ   +5 more
core  

Posttranslational remodeling micelle reverses cell-surface and exosomal PD-L1 immunosuppression in tumors resistant to PD-L1 antibody therapy

open access: hybrid
Xuetao Shi   +10 more
openalex   +1 more source

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