Advances in Immunosuppressive Agents Based on Signal Pathway [PDF]
Frontiers in Pharmacology, 2022 Immune abnormality involves in various diseases, such as infection, allergic diseases, autoimmune diseases, as well as transplantation. Several signal pathways have been demonstrated to play a central role in the immune response, including JAK/STAT, NF ...
Zhiqing Xu, Zhiqing Xu, Ming Chu
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Nonimmunologic targets of immunosuppressive agents in podocytes
Kidney Research and Clinical Practice, 2015 Proteinuria is a characteristic finding in glomerular diseases and is closely associated with renal outcomes. In addition, therapeutic interventions that reduce proteinuria improve renal prognosis.
Tae-Hyun Yoo, Alessia Fornoni
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Live attenuated vaccines in patients receiving immunosuppressive agents. [PDF]
Pediatr Nephrol, 2023 The use of live attenuated vaccines in patients with immunosuppressive agents is contraindicated in package inserts and guidelines in Japan and other countries.
Kamei K.
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Immunosuppressive Agents and Infectious Risk in Transplantation: Managing the "Net State of Immunosuppression". [PDF]
Clin Infect Dis, 2021 Successful solid organ transplantation reflects meticulous attention to the details of immunosuppression, balancing risks for graft rejection against risks for infection.
Roberts MB, Fishman JA.
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Failure of primary immunosuppressive agents in uveitis [PDF]
Indian Journal of OphthalmologyPurpose: This retrospective study aimed to evaluate the effectiveness of various immunomodulatory therapy (IMT) regimens in managing non-infectious uveitis (NIU) and to identify optimal treatment strategies for refractory cases.
Ankush Kawali +4 more
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Early tapering of immunosuppressive agents after HLA-matched donor transplantation can improve the survival of patients with advanced acute myeloid leukemia [PDF]
Annals of Hematology, 2017 Disease recurrence is the most important obstacle to achieve long-term survival for patients with advanced acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Jun J. Yang +8 more
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Immunosuppressive agents for treating IgA nephropathy. [PDF]
Cochrane Database Syst Rev, 2020 BACKGROUND IgA nephropathy is the most common glomerulonephritis world-wide. IgA nephropathy causes end-stage kidney disease (ESKD) in 15% to 20% of affected patients within 10 years and in 30% to 40% of patients within 20 years from the onset of disease.
Natale P +9 more
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Efficacy of Tripterygium glycosides in immune-mediated kidney diseases as a immunomodulation drug in combination with conventional immunosuppressive agents: a systematic review and meta-analysis of randomized controlled trials [PDF]
Frontiers in PharmacologyBackgroundImmune-mediated kidney diseases involve the immune system attacking the kidneys, resulting in damage and dysfunction. Tripterygium glycosides (TG) are known for their strong immunosuppressive and anti-inflammatory effects and are commonly used ...
Yaotan Li +14 more
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Simplified immunosuppressive and neuroprotective agents based on gracilin A [PDF]
Nature Chemistry, 2019 The architecture and bioactivity of natural products frequently serve as embarkation points for the exploration of biologically relevant chemical space.
M. Abbasov +9 more
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New immunosuppressive agents in pediatric transplantation
Clinics, 2014 Immunosuppressive therapy in pediatrics continues to evolve. Over the past decade, newer immunosuppressive agents have been introduced into adult and pediatric transplant patients with the goal of improving patient and allograft survival.
Christina Nguyen, Ron Shapiro
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