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Surgical Clinics of North America, 1994
The present success of organ transplantation is largely due to advances in immunosuppressive therapy. Progress has been made from a cytotoxic strategy associated with a high morbidity rate to a strategy that seeks to alter the activity of cells that regulate the immune response, in order to selectively dampen antidonor responses.
B D, Kahan, R, Ghobrial
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The present success of organ transplantation is largely due to advances in immunosuppressive therapy. Progress has been made from a cytotoxic strategy associated with a high morbidity rate to a strategy that seeks to alter the activity of cells that regulate the immune response, in order to selectively dampen antidonor responses.
B D, Kahan, R, Ghobrial
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Gastroenterology Clinics of North America, 1993
In summary, many new modalities of immunosuppression after transplantation are being investigated (Fig. 1). These approaches include various new drugs or monoclonal antibodies that target different cell subsets, cellular activation pathways, cellular effector function or mediators (such as cytokines) of effector function, ligands that stabilize ...
G L, Bumgardner, J P, Roberts
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In summary, many new modalities of immunosuppression after transplantation are being investigated (Fig. 1). These approaches include various new drugs or monoclonal antibodies that target different cell subsets, cellular activation pathways, cellular effector function or mediators (such as cytokines) of effector function, ligands that stabilize ...
G L, Bumgardner, J P, Roberts
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New agents for immunosuppression
Best Practice & Research Clinical Gastroenterology, 2021The human abdomen harbors organs that the host's immune system can attack easily. This immunological storm front leads to diseases like Crohn's Disease, Ulcerative Colitis or Autoimmune Hepatitis. Serious symptoms like pain, diarrhea, fatigue, or malnutrition accompany these diseases.
André Jefremow, Markus F. Neurath
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Immunosuppressive Agents in Dermatology
Dermatologic Clinics, 1993Azathioprine, cyclophosphamide, and cyclosporine are immunosuppressive agents commonly used by dermatologists. Azathioprine has a good safety profile and is preferred by most dermatologists for the treatment of bullous pemphigoid, cutaneous vasculitides, chronic eczematous dermatitides, and cutaneous manifestations of connective tissue diseases.
V C, Ho, D M, Zloty
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Immunosuppressive agents and asthma
Clinical Reviews in Allergy, 1994One of the goals of asthma therapy is to maintain control of symptoms without producing unwanted effects from asthma medications. Corticosteroids are the mainstay for intractable chronic asthma, but their long-term use in high doses is limited by the risk of significant adverse effects.
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Glucocorticosteroids as immunosuppressive agents
Seminars in Veterinary Medicine and Surgery: Small Animal, 1997When administered at pharmacological dosages, glucocorticosteroid hormones alter leukocyte kinetics, phagocytic cell function, cell-mediated immunity, and, to a lesser extent, humoral immunity. These properties are used to advantage in the treatment of immunologically mediated disease.
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