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Advances in Immunosuppressive Agents Based on Signal Pathway [PDF]

open access: yesFrontiers in Pharmacology, 2022
Immune abnormality involves in various diseases, such as infection, allergic diseases, autoimmune diseases, as well as transplantation. Several signal pathways have been demonstrated to play a central role in the immune response, including JAK/STAT, NF ...
Zhiqing Xu, Zhiqing Xu, Ming Chu
doaj   +2 more sources

Failure of primary immunosuppressive agents in uveitis [PDF]

open access: yesIndian Journal of Ophthalmology
Purpose: This retrospective study aimed to evaluate the effectiveness of various immunomodulatory therapy (IMT) regimens in managing non-infectious uveitis (NIU) and to identify optimal treatment strategies for refractory cases.
Ankush Kawali   +4 more
doaj   +2 more sources

Efficacy of Tripterygium glycosides in immune-mediated kidney diseases as a immunomodulation drug in combination with conventional immunosuppressive agents: a systematic review and meta-analysis of randomized controlled trials [PDF]

open access: yesFrontiers in Pharmacology
BackgroundImmune-mediated kidney diseases involve the immune system attacking the kidneys, resulting in damage and dysfunction. Tripterygium glycosides (TG) are known for their strong immunosuppressive and anti-inflammatory effects and are commonly used ...
Yaotan Li   +14 more
doaj   +2 more sources

Case report: Managing pemphigus foliaceus using apremilast without systemic glucocorticosteroids or immunosuppressive agents [PDF]

open access: yesFrontiers in Immunology
Pemphigus foliaceus (PF) is a superficial form of pemphigus. Treatment options for PF resemble pemphigus vulgaris, including glucocorticosteroids, immunosuppressive agents and rituximab et al.
Quanhong Zhang   +8 more
doaj   +2 more sources

Actinomycosis in a Mucosal Lesion on a Created Perioral Dimple: A Case Report [PDF]

open access: yesArchives of Aesthetic Plastic Surgery, 2017
Facial dimple creation is a simple surgical procedure. Nonetheless, several complications can occur. Actinomycosis is a rare chronic granulomatous infection caused by Actinomyces species.
Ui Geon Kim   +3 more
doaj   +1 more source

Immunosuppressive therapy in non-infections uveitis and retinovasculitis

open access: yesOftalʹmologiâ, 2014
Purpose: to evaluate the efficacy and safety of the immunosuppressive therapy for severe forms of non-infections uveitis and retinovasculitis.Methods: 107 patients (62 males and 45 females aged 9 to 54 years) who received low dose methotrexate — 7.5-20 ...
E. A. Drozdova
doaj   +3 more sources

Safety and effectiveness of mycophenolate mofetil associated with tacrolimus for liver transplantation immunosuppression: a systematic review and meta-analysis of randomized controlled trials [PDF]

open access: yesClinics, 2021
A combination of immunosuppressants may improve outcomes due to the synergistic effect of their different action mechanisms. Currently, there is no consensus regarding the best immunosuppressive protocol after liver transplantation.
Francisco Tustumi   +11 more
doaj   +1 more source

Efficacy and safety of immunosuppressive treatment in IgA nephropathy: a meta-analysis of randomized controlled trials

open access: yesBMC Nephrology, 2019
Background Immunosuppressive agents have been widely used in the treatment of IgA nephropathy (IgAN), but the efficacy and safety remain controversial.
Zheng Zhang   +3 more
doaj   +1 more source

New drugs, new challenges for dermatologists: mucocutaneous ulcers secondary to everolimus [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
Everolimus, a mammalian target of rapamycin inhibitor, is an emerging drug, which is being increasingly applied in oncology and solid organ transplantation. Oral ulcers are a frequent side effect associated with this immunosupressor.
Victor Pavan Pasin   +5 more
doaj   +1 more source

New-onset epilepsy in a patient with myelin oligodendrocyte glycoprotein antibodies [PDF]

open access: yesEncephalitis, 2021
In the literature, several adult cases with myelin oligodendrocyte glycoprotein (MOG) antibodies (Abs)-associated disorders have been reported to have seizure and acute disseminated encephalomyelitis (ADEM) as the main clinical manifestations, but the ...
Hansol Im, Taewon Kim
doaj   +1 more source

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