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Advances in Immunosuppressive Agents Based on Signal Pathway [PDF]

open access: yesFrontiers in Pharmacology, 2022
Immune abnormality involves in various diseases, such as infection, allergic diseases, autoimmune diseases, as well as transplantation. Several signal pathways have been demonstrated to play a central role in the immune response, including JAK/STAT, NF ...
Zhiqing Xu, Zhiqing Xu, Ming Chu
doaj   +3 more sources

New immunosuppressive agents in pediatric transplantation [PDF]

open access: yesClinics, 2014
Immunosuppressive therapy in pediatrics continues to evolve. Over the past decade, newer immunosuppressive agents have been introduced into adult and pediatric transplant patients with the goal of improving patient and allograft survival.
Christina Nguyen, Ron Shapiro
doaj   +6 more sources

Immunosuppressive Agents and Infectious Risk in Transplantation: Managing the "Net State of Immunosuppression". [PDF]

open access: yesClin Infect Dis, 2021
Successful solid organ transplantation reflects meticulous attention to the details of immunosuppression, balancing risks for graft rejection against risks for infection.
Roberts MB, Fishman JA.
europepmc   +2 more sources

La terapia immunosoppressiva nel trapianto di rene [PDF]

open access: yesGiornale di Clinica Nefrologia e Dialisi, 2019
Immunosuppressive therapy in renal transplantation can be distinguished in induction therapy and maintenance therapy. Induction therapy is an intense immunosuppressive therapy administered at the time of kidney transplantation to reduce the risk of acute
Aris Tsalouchos, Maurizio Salvadori
doaj   +3 more sources

Immunosuppressive agents for treating IgA nephropathy. [PDF]

open access: yesCochrane Database Syst Rev, 2020
BACKGROUND IgA nephropathy is the most common glomerulonephritis world-wide. IgA nephropathy causes end-stage kidney disease (ESKD) in 15% to 20% of affected patients within 10 years and in 30% to 40% of patients within 20 years from the onset of disease.
Natale P   +9 more
europepmc   +2 more sources

Drug Interactions between Antimicrobial and Immunosuppressive Agents in Solid Organ Transplant Recipients.

open access: yesIndian J Crit Care Med, 2021
The number of allogeneic solid organ and bone marrow transplants is increasing all over the world. To prevent transplant rejection and treat acute rejection of transplant, immunosuppressant drugs are used.
Bhagat V   +4 more
europepmc   +2 more sources

Pharmacokinetics of immunosuppressive agents during hemoperfusion in a sheep model [PDF]

open access: yesFrontiers in Medicine, 2023
IntroductionHemoadsorption shows promising signals in organ preservation and post lung transplantation. However, its potential impact on the pharmacokinetics of immunosuppressant drugs (ID) is still unknown.MethodsIn this interventional study, CytoSorb ...
Bettina Leber   +7 more
doaj   +2 more sources

Case report: Managing pemphigus foliaceus using apremilast without systemic glucocorticosteroids or immunosuppressive agents [PDF]

open access: yesFrontiers in Immunology
Pemphigus foliaceus (PF) is a superficial form of pemphigus. Treatment options for PF resemble pemphigus vulgaris, including glucocorticosteroids, immunosuppressive agents and rituximab et al.
Quanhong Zhang   +8 more
doaj   +2 more sources

Nonimmunologic targets of immunosuppressive agents in podocytes

open access: yesKidney Research and Clinical Practice, 2015
Proteinuria is a characteristic finding in glomerular diseases and is closely associated with renal outcomes. In addition, therapeutic interventions that reduce proteinuria improve renal prognosis.
Tae-Hyun Yoo, Alessia Fornoni
doaj   +2 more sources

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