Results 121 to 130 of about 174,772 (308)

Vitiligo Signature‐Based Drug Screening Identifies Fulvestrant as a Novel Immunotherapy Combination Strategy

open access: yesAdvanced Science, EarlyView.
A vitiligo‐derived gene signature predicts response to immune checkpoint blockade across multiple cancer cohorts, providing a framework for patient stratification. Building on this, Fulvestrant—a clinically approved estrogen receptor degrader—further enhances antitumor immunity by reprogramming tumor‐associated macrophages and promoting CD8⁺ T cell ...
Jie Zhu   +8 more
wiley   +1 more source

Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

open access: yesAdvanced Science, EarlyView.
Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu   +18 more
wiley   +1 more source

Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents. [PDF]

open access: yesJ Enzyme Inhib Med Chem, 2022
Walczak JM   +6 more
europepmc   +1 more source

Therapeutic effects of FTY720, a new immunosuppressive agent, in a murine model of acute viral myocarditis [PDF]

open access: green, 2001
Tadashi Miyamoto   +5 more
openalex   +1 more source

Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy

open access: yesAdvanced Science, EarlyView.
An Escherichia coli bacterial biorobot is engineered for localized microwave activation in cancer therapy. Upon activation at tumor sites, the biorobot releases glucose oxidase, inducing tumor cell death via glucose depletion and H2O2 generation catalyzed by Cu2O.
Huilan Zhuang   +9 more
wiley   +1 more source

Immunogenicity and safety of SARS-CoV-2 vaccine with immunosuppressive agents. [PDF]

open access: yesPediatr Int, 2022
Kamei K   +7 more
europepmc   +1 more source

Comparison of cyclophosphamide, cytarabine, and etoposide as immunosuppressive agents before allogeneic bone marrow transplantation

open access: bronze, 1988
Walter Gassmann   +5 more
openalex   +1 more source

Glabridin‐Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Complex 6d could promote tumor immunogenicity by targeting thioredoxin reductase (TrxR) and remodel immunosuppressive microenvironment by the mitogen‐activated protein kinase (MAPK) pathway inhibition simultaneously. This study provides a novel approach to develop metal immunomodulatory agents by designing gold complexes incorporating natural products,
Zhaoran Wang   +10 more
wiley   +1 more source

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