Results 121 to 130 of about 254,031 (357)

Organic AIE Nanoradiosensitizer Potentiates X‐Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy

open access: yesAdvanced Materials, EarlyView.
Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu   +10 more
wiley   +1 more source

IMMUNOSUPPRESSIVE AGENT CYCLOSPORIN A AND VARIOUS CELL GROWTH FACTORS AFFECT CLONED OSTEOBLASTIC CELL LINE MC3T3-E1 CELLS [PDF]

open access: bronze, 1988
K. Okano   +11 more
openalex   +1 more source

Self‐Powered α Radionuclide Nanomedicine: Mitochondria‐Targeted Multimodal Energy Recycling for Amplified Radioimmunotherapy

open access: yesAdvanced Materials, EarlyView.
A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li   +7 more
wiley   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

A Programmable Nanovaccine Platform Based on M13 Bacteriophage for Personalized Cancer Vaccine and Therapy

open access: yesAdvanced Materials, EarlyView.
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang   +10 more
wiley   +1 more source

THE PROLONGATION OF CANINE RENAL HOMOGRAFT FUNCTION USING ANTILYMPHOCYTE SERUM AS AN IMMUNOSUPPRESSIVE AGENT

open access: bronze, 1967
Russell K. Lawson   +3 more
openalex   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

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