Results 151 to 160 of about 174,772 (308)

MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

Advanced Science, EarlyView.
Herbal medicine, with its multicomponent and multitarget potential, is often studied primarily for traditional forms, especially phytochemicals. Currently, ulcerative colitis lacks natural, low‐toxicity therapies, yet emerging research highlights plant‐derived exosomes as a promising option.
Ruipeng Shi, Wen Tan, Haochun Jin, Sio I Chan, Wei Li, Si San Lei, Guozhen Cui, Yitao Wang, Dong‐Hua Yang, Zhangfeng Zhong   +9 more
wiley   +1 more source

Comparative the efficacy and acceptability of immunosuppressive agents for myasthenia gravis: A protocol for systematic review and network meta-analysis. [PDF]

Medicine (Baltimore), 2022
Xu P, Zhang Y, Chang T, Jiang L, Lv Z, Zhang Y, Xu H, Zhang D, Lan T, Cui Y, Hua Z, Gao C, Lu J, Huang Q, Tian J, Ma J, Wang J.   +16 more
europepmc   +1 more source

Chronopharmacokinetic Study of a New Immunosuppressive Agent, FK 506, in Mice

, 1993
Akio Fujimura, Tsuyoshi Shiga, Kyoichi Ohashi, Akio Ebihara   +3 more
openalex   +1 more source

Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR‐NFκB Pathway

Advanced Science, EarlyView.
This study demonstrates that vinburnine, an approved cerebrovascular drug, synergizes with radiotherapy in nasopharyngeal carcinoma (NPC) by modulating EDAR‐NFκB signaling through directly binding to EDAR, leading to triggering apoptosis/pyroptosis, and amplifying CCL5/CX3CL1‐driven T‐cell cytotoxicity.
Jing Chen, Nian Liu, Qian Tao, Jie Wu, Jinyu Huang, Can Lu, Qiuqiu Li, Liangfang Shen, Xiang Chen, Cong Peng   +9 more
wiley   +1 more source

Treatment of systemic lupus erythemus overlap syndrome with autoimmune hepatitis using a combination of glucocorticoids and immunosuppressive agents: Case report. [PDF]

Medicine (Baltimore)
Li Z, Zha Z, Zhang S, Jiang T, Wu Y, Lu W, Li Y, Liu J, Lin L.   +8 more
europepmc   +1 more source

Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents. [PDF]

Case Rep Pathol, 2022
Okano S, Yao T, Nomura O, Nagahara A, Hagiwara T, Sugimoto K, Takahashi M, Sakamoto K.   +7 more
europepmc   +1 more source

A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells [PDF]

, 2003
Yumiko Matsuoka, Yukitoshi Nagahara, Masahiko Ikekita, Takahisa Shinomiya   +3 more
openalex   +1 more source

Lactate Activates the HCAR1/β‐Arrestin2/PP2A Signaling Axis to Mediate STAT1/2 Dephosphorylation and Drive Osteosarcoma Progression

Advanced Science, EarlyView.
In the present study, it is found that in osteosarcoma, lactate‐activated HCAR1 promotes β‐arrestin 2 translocation from cytoplasm to nucleus. In the nucleus, β‐arrestin 2 recruits PP2A to the activated STAT1/2 dimers, mediating STAT1/2 dephosphorylation and inhibiting the transcription of downstream anti‐oncogenes to promote OS progression.
Zhitao Han, Qi Jia, Guangjian Bai, Zhao Li, Jin Zeng, Zhenhua Wang, Jing Zhang, Jiashi Cao, Baoquan Xin, Yonggang Liu, Jingyu Shen, Lining Wang, Xing Huang, Chunlei Zhang, Kai Tong, Fenglei Dai, Yajie Zhang, Weina Zhu, Songyi Cheng, Yuanming Chen, Xinghai Yang, Guanghui Chen, Zhenhua Zhou, Yong Ma, Weibo Liu, Ting Wang, Tielong Liu   +26 more
wiley   +1 more source

Th17 cell function in cancers: immunosuppressive agents or anti-tumor allies? [PDF]

Cancer Cell Int
Anvar MT, Rashidan K, Arsam N, Rasouli-Saravani A, Yadegari H, Ahmadi A, Asgari Z, Vanan AG, Ghorbaninezhad F, Tahmasebi S.   +9 more
europepmc   +1 more source

Comparison of effects of aminosalicylic acid, glucocorticoids and immunosuppressive agents on the expression of multidrug-resistant genes in ulcerative colitis. [PDF]

Sci Rep, 2022
Chen Y, Wang P, Zhang Y, Du XY, Zhang YJ.   +4 more
europepmc   +1 more source