Results 161 to 170 of about 276,669 (295)

Management of Proteinuria in Dogs and Cats with Chronic Kidney Disease [PDF]

, 2016
Atkins, Bakris, Bianchi, Bomback, Brown, Brown, Brown, Brown, Bugbee, Christ, Finco, Grauer, Grauer, Horita, Jacob, Jenkins, Jepson, Jepson, Jonathan Elliott, King, King, Laverman, Lees, Lefebvre, LeVine, Linas, Littman, Maack, McAlister, Mizutani, Nabity, Nakamura, Pollock, Pressler, Ryan, Schjoedt, Schneider, Segev, Segev, Sent, Shelly L. Vaden, Singh, Syme, Tenhundfeld, Toblli, Vaden, Wehner   +46 more
core   +2 more sources

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

Advanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu, Shanjia Ke, Hongjun Yu, Zhanzhi Meng, Miaoyu Bai, Yanan Xu, Hui Zhu, Jinwen Yang, Baolin Qian, Bing Yin, Chaoqun Wang, Zhigang Feng, Zhongyu Li, Yongzhi Zhou, Zihao Li, Xinglong Li, Yongliang Hua, Yao Fu, Wei Tang, Yaohua Wu, Yong Ma   +20 more
wiley   +1 more source

Efficacy of Rituximab as Adjunctive Therapy to Immunosuppressive Agents in Adult Primary Focal Segmental Glomerulosclerosis. [PDF]

Kidney Int Rep
Mohamed ON, Mohamed MI, Mohammed Elsaghir SM, Abdelrazek S, Azzam A, Senosy Mohamed TM, Mohammed HMH, Yousef R, Abd Rabou AA, Abdelazeem Elgarhy RY, Mohamed Mahdy AK, Abdelsamie MA, Sayed MM, Fathi E, Mohammed Toni ND, Saleh RK, Fathy B.   +16 more
europepmc   +1 more source

Microsponge-derived mini tablets loaded with immunosuppressive agents: Pharmacokinetic investigation in human volunteers, cell viability and IVIVC correlation. [PDF]

Saudi Pharm J, 2023
Mehmood Y, Shahid H, Abbas M, Farooq U, Farooq U, Ali S, Kazi M.   +6 more
europepmc   +1 more source

Clinical use of immunosuppressants [PDF]

, 2005
Fung, JJ, Schonder, KS, Starzl, TE, Weber, RJ   +3 more
core  

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents. [PDF]

Case Rep Pathol, 2022
Okano S, Yao T, Nomura O, Nagahara A, Hagiwara T, Sugimoto K, Takahashi M, Sakamoto K.   +7 more
europepmc   +1 more source

The organ transplanted patient - immunological concepts and immunosuppression [PDF]

, 1991
Husberg, BS, Klintmalm, GBG, Starzl, TE
core  

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, Volume 13, Issue 31, 4 June 2026.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Complications Associated with Immunosuppressive Agents in Solid Organ Transplant Recipients: A Nationwide Analysis. [PDF]

J Clin Med
Lee AY, Jeong J, Heo KN, Park S, Ah YM, Han JM, Lee JY, Min SI.   +7 more
europepmc   +1 more source