Results 151 to 160 of about 276,669 (295)

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

Prognostic benefit of immunosuppressive agents in primary Sjögren's syndrome patients with hypergammaglobulinemia. [PDF]

Front Immunol
Zhang L, Zou Y, Chen D, Zhang X, Jia Z, Zhang Q, Wang F, Feng X.   +7 more
europepmc   +1 more source

Sequential Treatment by Antiviral Drugs Followed by Immunosuppressive Agents for COVID-19 Patients with Hematological Malignancy. [PDF]

Infect Drug Resist, 2022
Seki M, Hashimoto K, Kondo N, Ohya Y, Kotajima F, Mitsutake K.   +5 more
europepmc   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Immunosuppressive agents in diabetes treatment: Hope or despair? [PDF]

World J Diabetes
Li L, Yang X, Ren JS, Huang MZ, Zhao QW.
europepmc   +1 more source

The relationship between cumulative dose of immunosuppressive agents and COVID-19-associated mucormycosis: A multicenter cross-sectional study. [PDF]

Health Sci Rep, 2022
Rastkar M, SeyedAlinaghi S, Asanjarani B, Siri G, Abdollahi H, Ghadami L, Hasibi M, Khodashahi R, Bagheri A, Asadollahi-Amin A.   +9 more
europepmc   +1 more source

Notes on some immunosuppressive agents and their use in human liver transplant recipients [PDF]

, 1974
Groth, CG, Halgrimson, CG, Husberg, B, Kashiwagi, N, Penn, I, Putnam, CW, Starzl, TE   +6 more
core  

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

A case of localized abdominal aortic dissection secondary to retroperitoneal fibrosis cured only with glucocorticoids and immunosuppressive agents. [PDF]

Quant Imaging Med Surg, 2023
Zhang C, Liu Y, Ma N.
europepmc   +1 more source

New immunosuppressive drugs: Mechanisms of action and early clinical experience [PDF]

, 1993
Fung, JJ, Shapiro, R, Starzl, TE, Thomson, AW   +3 more
core