Results 151 to 160 of about 6,220 (295)

Predictors and long-term impact of sustained complete renal response in lupus nephritis patients over a median 10-year follow-up. [PDF]

Rheumatology (Oxford)
Michelakis IE, Kapsia E, Boletis JN, Marinaki S, Sfikakis PP, Tektonidou MG.   +5 more
europepmc   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

HAVCR2 in subcutaneous panniculitis-like T cell lymphoma: comment on the article by Chambers et al. [PDF]

Arthritis Rheumatol
Chen AAY, Schwarzkopf R, Schrader KA, Chen LYC.   +3 more
europepmc   +1 more source

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

Management of major organ involvement in Behçet syndrome: a systematic literature review informing the 2025 update of the EULAR recommendations. [PDF]

EULAR Rheumatol Open
Ozguler Y, Esatoglu SN, Tomasson G, Falzon L, Barete S, Bettiol A, Bodaghi B, Boyadzhieva V, Cantarini L, Celik AF, Dhrif O, Ducker G, Emmi G, Gül A, Henes J, Koetter I, Krusche M, Lopalco G, Moots R, Saadoun D, Salvarani C, Sfikakis P, Stefanovic A, Talarico R, Tugal-Tutkun I, Uygunoglu U, Zhao Q, Ramiro S, Hatemi G.   +28 more
europepmc   +1 more source

Immunosuppressives in Sarcoidosis

, 1985
Patricia Leong, Linda L. Hart
core   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Alert Card for Patients on Biologicals and Immunosuppressives: An EAACI Position Paper. [PDF]

Allergy
Chaker A, Kauppi P, Bavbek S, Bossios A, Chatzipetrou A, Firinu D, Rogala B, Matucci A, Vultaggio A, Panzner P, Feleszko W, Eliashar R, Agache I, Klimek L, Torres M, Pfaar O, Palomares O, Shamji M, Eiwegger T, Kolios AGA.   +19 more
europepmc   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Targeting the BlyS/APRIL axis in neuro-Behçet disease: a rationale for telitacicept as a steroid-sparing strategy. [PDF]

Ann Med Surg (Lond)
Qaseem M, Hassan MU, Khan AM, Mustafa A, Fatima M.   +4 more
europepmc   +1 more source