Results 111 to 120 of about 944,744 (294)

Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer. [PDF]

, 2017
BackgroundT cells engineered to express chimeric antigen receptors (CARs) have established efficacy in the treatment of B-cell malignancies, but their relevance in solid tumors remains undefined.
A Molinolo, A Stasi Di, A Thor, B Fisher, BA Irving, BL Levine, C Romeo, CC Kloss, CY Wu, D Moritz, DL Porter, DW Lee, F Guadagni, HM Finney, I Blanco, I Stancovski, J Scholler, JD Wolchok, JL Murray, JN Kochenderfer, JW Greiner, KD Griffith, L Naldini, M Hegde, M Kalos, ME Dudley, MH Finer, MH Kershaw, ML Davila, MR Lander, N Gonzales, NP Restifo, P Hwu, RA Morgan, RE Walker, RF Meredith, RP McGuinness, RT Mitsuyasu, S Guedan, SD Patel, SG Deeks, SL Maude, SV Kashmiri   +42 more
core   +1 more source

Loop Catalog: a comprehensive HiChIP database of human and mouse samples

Genome Biology
HiChIP enables cost-effective and high-resolution profiling of chromatin loops. To leverage the increasing number of HiChIP datasets, we develop Loop Catalog ( https://loopcatalog.lji.org ), a web-based database featuring loop calls from over 1000 ...
Joaquin Reyna, Kyra Fetter, Romeo Ignacio, Cemil Can Ali Marandi, Astoria Ma, Nikhil Rao, Zichen Jiang, Daniela Salgado Figueroa, Sourya Bhattacharyya, Ferhat Ay   +9 more
doaj   +1 more source

In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection [PDF]

, 2019
An overt pro-inflammatory immune response is a key factor contributing to lethal pneumococcal infection in an influenza pre-infected host and represents a potential target for therapeutic intervention.
Boehme, Julia D., Bruder, Dunja, Christen, Henrike, Guzmán, Carlos A., Hernandez-Vargas, Esteban A., Kershaw, Olivia, Schreiber, Jens, Sharma-Chawla, Niharika, Stegemann-Koniszewski, Sabine   +8 more
core   +1 more source

Clinical effectiveness of hymenoptera venom immunotherapy [PDF]

, 2013
Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors. Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters with the frequency of VIT failure during ...
Aberer, Werner, Biló, Maria Beatrice, Bodzenta-Lukaszyk, Anna, Bonifazi, Floriano, Campi, Paolo, Darsow, Ulf, Haeberli, Gabrielle, Hawranek, Thomas, Küchenhoff, Helmut, Lang, Roland, Müller, Ulrich, Przybilla, Bernhard, Quercia, Oliviero, Reider, Norbert, Ruëff, Franziska, Scheipl, Fabian, Schmid-Grendelmeier, Peter, Seitz, Michael J., Severino, Maurizio, Sturm, Gunter Johannes, Treudler, Regina, Wüthrich, Brunello   +21 more
core   +1 more source

Nivolumab-induced fulminant diabetic ketoacidosis followed by thyroiditis [PDF]

, 2018
Five days following the 3rd cycle of nivolumab, a monoclonal antibody, which acts as immune checkpoint inhibitor against the programmed cell death protein-1, for metastatic lung adenocarcinoma, a 56-year-old woman presented at the hospital critically ill.
Baker, E, Corbett, RW, Doulgeraki, T, Heaton, D, Ponnampalam, S, Stebbing, J, Tzoulis, P   +6 more
core   +2 more sources

Allergy Anaphylaxis and Immunotherapy [PDF]

, 1944

openalex   +1 more source

Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

Cell Stress, 2019
The TNF blockade therapy is currently a well-established treatment option for a variety of autoimmune diseases such as rheumatoid arthritis (RA), psoriasis or Crohn’s disease, given the proinflammatory role of TNF in the course of these diseases ...
Maite Alvarez, Itziar Otano, Luna Minute, Maria Carmen Ochoa, Elisabeth Perez-Ruiz, Ignacio Melero, Pedro Berraondo   +6 more
doaj   +1 more source

Preliminary experimentation with specific immunotherapy of neoplastic disease in man.I. Immediate effects of hyperimmune equine gamma globulins [PDF]

, 1963
Sergio de Carvalho
openalex   +1 more source

Allergen immunotherapy

Allergy, Asthma & Clinical Immunology
Abstract Allergen immunotherapy (AIT) is a potentially disease-modifying therapy that is effective for the treatment of allergic rhinitis/conjunctivitis, allergic asthma and stinging insect hypersensitivity. The decision to proceed with AIT should be made on a case-by-case basis, based on a comprehensive evaluation of the patient, allergy ...
Jean-Nicolas Boursiquot, Rémi Gagnon, Jaclyn Quirt, Anne K. Ellis   +3 more
openaire   +3 more sources

Adoptive Immunotherapy of Leukemia in the Rat, without Graft-vs-Host Complications [PDF]

, 1979
Owen Westcott, Susan E. Dorsch, Bruce Roser   +2 more
openalex   +1 more source