Results 101 to 110 of about 1,129,256 (278)

Fine Structure of Open Shell Diatomic Molecules in Combined Electric and Magnetic Fields

open access: yes, 2013
We present a theoretical study of the impact of an electric field combined with a magnetic field on the rotational dynamics of open shell diatomic molecules.
González-Férez, Rosario   +3 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Positron excitation of neon [PDF]

open access: yes
The differential and total cross section for the excitation of the 3s1P10 and 3p1P1 states of neon by positron impact were calculated using a distorted-wave approximation.
Mceachran, R. P.   +2 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Impact of Approximate Multipliers on VGG Deep Learning Network

open access: yesIEEE Access, 2018
This paper presents a study on the applicability of using approximate multipliers to enhance the performance of the VGGNet deep learning network. Approximate multipliers are known to have reduced power, area, and delay with the cost of an inaccuracy in output. Improving the performance of the VGGNet in terms of power, area, and speed can be achieved by
Issam Hammad, Kamal El-Sankary
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

$t\bar{t}t\bar{t}$: NLO QCD corrections in production and decays for the $3\ell$ channel

open access: yesSciPost Physics Proceedings
We discuss the results for the four-top quark production process at the LHC at NLO accuracy in perturbative QCD for the $3\ell$ decay channel. The QCD corrections are applied in both the production and the decay stages of the four top quarks by employing
Nikolaos Dimitrakopoulos
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The Impact of the Angle-average Approximation in the Partial Frequency Redistribution Modeling of the Mg ii h–k Doublet Stokes Profiles

open access: yesThe Astrophysical Journal
In recent years, the Mg  ii h and k lines have become increasingly important for the diagnostics of magnetic fields in the solar chromosphere, motivated both by the advances in the modeling capabilities of their polarization and by the unprecedented ...
Tanausú del Pino Alemán   +5 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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