Results 71 to 80 of about 1,129,256 (278)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Spread Option Pricing Under Finite Liquidity Framework

open access: yesRisks
This work explores a finite liquidity model to price spread options and assess the liquidity impact. We employ Kirk approximation for computing the spread option price and its delta.
Traian A. Pirvu, Shuming Zhang
doaj   +1 more source

Asymptotic approximation for the solution to a semi-linear elliptic problem in a thin aneurysm-type domain

open access: yesOpen Mathematics, 2017
A semi-linear boundary-value problem with nonlinear Robin boundary conditions is considered in a thin 3D aneurysm-type domain that consists of thin curvilinear cylinders that are joined through an aneurysm of diameter 𝓞(ε). Using the multi-scale analysis,
Mel’nyk Taras A.   +1 more
doaj   +1 more source

Approximation-Aware Design of an Image-Based Control System

open access: yesIEEE Access, 2020
Image-based control (IBC) systems are common in many modern applications. In such systems, image-based sensing imposes massive compute workload, making them challenging to implement on embedded platforms.
Sayandip De   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Survey of Results on the Limit -Bernstein Operator

open access: yesJournal of Applied Mathematics, 2013
The limit -Bernstein operator emerges naturally as a modification of the Szász-Mirakyan operator related to the Euler distribution, which is used in the -boson theory to describe the energy distribution in a -analogue of the coherent state.
Sofiya Ostrovska
doaj   +1 more source

Bias of using odds ratio estimates in multinomial logistic regressions to estimate relative risk or prevalence ratio and alternatives

open access: yesCadernos de Saúde Pública, 2014
Recent studies have emphasized that there is no justification for using the odds ratio (OR) as an approximation of the relative risk (RR) or prevalence ratio (PR).
Suzi Alves Camey   +4 more
doaj   +1 more source

Analysis of error propagation in particle filters with approximation

open access: yes, 2012
This paper examines the impact of approximation steps that become necessary when particle filters are implemented on resource-constrained platforms. We consider particle filters that perform intermittent approximation, either by subsampling the particles
Coates, Mark J., Oreshkin, Boris N.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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