Results 91 to 100 of about 11,607,943 (308)
Social impact assessment in the mining sector: Review and comparison of indicators frameworks
Resources policy, 2018 Mining provides inputs for other industrial sectors that are vital for sustaining population wellbeing and the functioning of global economies. At the same time, it can generate social and environmental impacts, which could compromise public acceptance ...
L. Mancini, Serenella Sala
semanticscholar +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Analysis of the technical quality of environmental impact studies done on the Atlantic Rain Forest of Santa Catarina: a faunistic approach [PDF]
Biotemas, 2011 Alterations in components of an ecosystem might modify ecological interactions, which are sometimes irreversible, and could cause a loss in biodiversity.
Marinez Scherer
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
WISEs’ Social Impact Measurement in the Baltic States
European Journal of Social Impact and Circular Economy, 2020 WISEs devote most of their time and resources to working with the target group - not only organizing their employment activities and developing skills but also adapting their work environment, improving the psychological climate, organizational culture ...
Audrone Urmanaviciene
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Short Communication - Aquatic Oil Pollution Impact Indicators
Journal of Applied Sciences and Environmental Management, 2005 Aquatic oil pollution impact indicators such as oil-grease, low dissolved oxygen concentration, increased biochemical oxygen demand, increased water temperature and acidity of the water are associated with aquatic habitat degradation, reduced ...
V N Enujiugha, L C Nwanna
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Factors Influencing Research Performance in Higher Education: An Empirical Investigation
Foresight and STI Governance, 2012 Universities play an increasingly significant role in producing new knowledge. The relationship between research inputs (grants, infrastructure spending, training of researchers) and research outputs (number of publications, citation, impact) emerges ...
Johann Jacob, Moktar Lamari
doaj +1 more source