Results 81 to 90 of about 11,607,943 (308)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Effects of sea bass and sea bream farming (Western Mediterranean Sea) on peracarid crustacean assemblages [PDF]

open access: yesAnimal Biodiversity and Conservation, 2011
Benthic soft-bottom assemblages are good indicators of environmental disturbance, such as coastal aquaculture, considering their rapid response in terms of diversity and abundance.
Fernandez–Gonzalez, V.   +1 more
doaj  

Contribution indicators of work stress and employee organizational commitments case study

open access: yesBusiness: Theory and Practice, 2019
This study aims to determine the contribution of work stress indicators as exogenous variables and organizational commitment as endogenous variables consisting of subvariable affective, continuance, and normative commitments. The sample of respondents in
Tuty Sariwulan   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Indicators of NBS performance and impact [PDF]

open access: yes, 2021
This chapter introduces 12 categories of societal challenges that NBS can address (Section 4.1). These are conceptually mapped against the UN Sustainable Development Goals. For each of the 12 societal challenge areas, Section 4.2 outlines and lists indicators to evaluate the performance and impact of NBS.
Dumitru, Adina   +6 more
  +5 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Sustainability of Circular Economy Indicators and Their Impact on Economic Growth of the European Union

open access: yesSustainability, 2019
In this paper, we develop a methodology for studying the sustainability of the circular economy model, based on environmental indicators, and its impact on European Union (EU) economic growth. In open-end systems, waste is converted back to materials and
Mihail Bușu, C. Trică
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Assessment of industrialised construction through sustainability tools

open access: yesResults in Engineering
The environmental impact of the construction sector and its importance to the economy makes the transition to a more sustainable model imperative. Industrialised construction can facilitate this transition.
Guillermo Sotorrío Ortega   +3 more
doaj   +1 more source

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