Results 131 to 140 of about 11,607,943 (308)
A review of microplastic presence in birds: Research advances and socioeconomic contexts
Environmental and Sustainability IndicatorsPlastics have become deeply embedded in modern society, with global production increasing more than 230-fold over the past seven decades, raising major ecological concerns. Plastic disperses across terrestrial, freshwater, and marine ecosystems via human
Laura-Elena Topală +4 more
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Revista Facultad Nacional de Agronomía Medellín, 2005 Se propuso el análisis estadístico multivariado para encontrar las relaciones entre variables e impactos, obtener una alta explicación e interpretación de sus causas y efectos y alcanzar el mayor grado de certidumbre posible, para calificar y clasificar ...
Jesús Efrén Ospina Noreña +1 more
doaj
Microplastic contamination of bryophytes: A review on mechanisms and impacts
HeliyonThis systematic review investigates the interactions of microplastics (MPs) and nanoplastics (NPs) with bryophytes, incorporating findings from 11 articles identified through a comprehensive database search using a combination of keywords.
Weerachon Sawangproh
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Key crops for processed foods have spatially variable biodiversity impacts not captured in other environmental impact indicators. [PDF]
Sci RepPamatat F +5 more
europepmc +2 more sources
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source