Results 161 to 170 of about 19,680 (211)
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
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Detection, mining and forecasting of impact load in power load forecasting
Applied Mathematics and Computation, 2005zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jianzhou Wang
exaly +3 more sources
The impact of standardized footwear on load and load symmetry
Clinical Biomechanics, 2021The inability to standardize footwear is a potential issue when measuring landing kinetics in non-laboratory settings. This study determined the impact of not standardizing footwear on load and load symmetry during landing. A secondary purpose of this study was to introduce the Load Analysis Program, an open-source MATLAB® user-interface for computing ...
Adam R, Luftglass +3 more
openaire +2 more sources
2022
Abstract This article reviews the impact response of plastic components and the various methods used to evaluate it.. It describes the effects of loading rate on polymer deformation and the influence of temperature and strain rate on failure mode.
Zoltán Major +2 more
openaire +1 more source
Abstract This article reviews the impact response of plastic components and the various methods used to evaluate it.. It describes the effects of loading rate on polymer deformation and the influence of temperature and strain rate on failure mode.
Zoltán Major +2 more
openaire +1 more source
Impacts of load reduction offers on load profile
2011 10th International Conference on Environment and Electrical Engineering, 2011Demand Response (DR) has gained so much importance due to its effect on load profile characteristics. The focus of this paper is on impacts of flexible load participation in day-ahead energy market, in which bulk power consumers introduce their load reduction as generation.
Javad Mohammadi +3 more
openaire +1 more source
The impact of cognitive load on reward evaluation
Brain Research, 2015The neural systems that afford our ability to evaluate rewards and punishments are impacted by a variety of external factors. Here, we demonstrate that increased cognitive load reduces the functional efficacy of a reward processing system within the human medial-frontal cortex.
Olave E. Krigolson +3 more
openaire +2 more sources