Results 41 to 50 of about 499,828 (261)
Meitan xuebaoDeep underground project takes place in an environment characterised by high water pressure and geostress. This poses a significant risk of disasters such as water surges and destabilisation of the peripheral rock body, especially under dynamic ...
Jiefang JIN +5 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Vertical Response of Stress Transmission Through Sand–Tire Mixture Under Impact
BuildingsThis study evaluates the vertical stress transmission through a sand–tire mixture layer under impact, focusing on this innovative blended material that can impact underground structures such as tunnels or pipelines.
Xingzhong Nong +5 more
doaj +1 more source
Engineering Applications of Computational Fluid Mechanics, 2021 In this study, we simulate the acceleration-induced cavity bubble expansion and its non-spherical collapse in a drastically varying pressure field caused by mechanical impact, and we qualitatively compare the results with those for similar ζ number ...
Yue-han Chen, Jie-min Zhan, Yu-tian Li
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Science and Engineering of Composite Materials, 2017 The current experimental study investigates impact response features of reinforced concrete (RC) beams with dominant shear failure mode. Six built nonstrengthened and strengthened RC beams with a shear span-to-depth ratio of 2.5 were subject to repeated ...
Shafei Erfan
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Dynamic responses analysis of submerged floating tunnel under impact load
BrodogradnjaSubmerged floating tunnel (SFT) may be subjected to sudden impact loads such as submarine and shipwreck. Besides the local damage caused by impact, the overall transient dynamic response may also affect its driving safety.
Ming Wang +5 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source