Results 91 to 100 of about 287,814 (303)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Going underground [PDF]

open access: yes, 2009
Malta has a serious nitrate pollution problem. But where is it all coming from?
Stuart, Marianne
core  

Collective navigation of complex networks: Participatory greedy routing

open access: yes, 2016
Many networks are used to transfer information or goods, in other words, they are navigated. The larger the network, the more difficult it is to navigate efficiently.
Helbing, Dirk, Kleineberg, Kaj-Kolja
core   +1 more source

Impact of Culture Condition Modulation on the High-Yield, High-Specificity, and Cost-Effective Production of Terpenoids from Microbial Sources: a Review

open access: yesApplied and Environmental Microbiology, 2020
Recent years have seen a remarkable increase in the nonnatural production of terpenoids by the microbial route. This is due to advancements in synthetic biology tools and techniques, which have overcome the challenges associated with the nonnative ...
Vibha Shukla, S. Phulara
semanticscholar   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Microbially Induced Mineralization of Layered Mn Oxides Electroactive in Li Batteries

open access: yesFrontiers in Microbiology, 2020
Nanoparticles produced by bacteria, fungi, or plants generally have physicochemical properties such as size, shape, crystalline structure, magnetic properties, and stability which are difficult to obtain by chemical synthesis.
Laura Galezowski   +8 more
doaj   +1 more source

Effect of Thiols for Nitrogen Reduction to Ammonia [PDF]

open access: yes, 2019
Ammonia is an important chemical used for fertilizers and also a potential carbon-free hydrogen storage medium. The Haber-Bosch process is the main production process, which requires large energy- and capital-input. Therefore, it is crucial to develop an
Ford, Zakary R.
core   +2 more sources

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Data-Driven Approach for Passenger Assignment in Urban Rail Transit Networks: Insights From Passenger Route Choices and Itinerary Choices

open access: yesJournal of Advanced Transportation
Congestion in urban rail transit (URT) systems often results in passengers being left behind on platforms due to trains’ reaching capacity. Distinguishing between the travel choice behaviors of passengers who board the first arriving train (Type I ...
Di Wen, Hongxia Lv, Hao Yu
doaj   +1 more source

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