Results 71 to 80 of about 175,975,280 (226)

A novel synthetic route to small-ring monostannacycloalkanes

, 1974
A novel synthetic route to small-ring monostannacycloalkanes, involving the intramolecular disproportionation of α, ω-bis(trialkylstannyl)alkanes, is ...
E.J. Bulten, Bulten, E.J., Budding, H.A., H.A. Budding   +3 more
core   +2 more sources

A bacterial route for folic acid supplementation

BMC Biology, 2018
Background To prevent folate deficiencies, many countries supplement various foodstuffs with folic acid. This compound is a synthetic oxidised folate that differs from naturally occurring reduced folates in its metabolism and uptake.
Claire Maynard, Ian Cummins, Jacalyn Green, David Weinkove   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Green production of multi-functional carbon dots from agricultural corn silk waste: application in heavy metal (Fe3+/Cu2+) fluorometric sensing and in vitro cytotoxicity

Scientific Reports
Corn silk (CS), an abundant agricultural waste, is typically converted into carbon dots (CDs) through energy-intensive methods such as hydrothermal treatment and microwave-assisted synthesis.
Dina Abdelmonsef, Sherif Hammad, Mohsen Ghali   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

A General Synthetic Route to Enantiopure 5-Substituted cis-Decahydroquinolines [PDF]

, 2017
A practical synthetic route to enantiopure 5-substituted cisdecahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of 2-substituted 6-oxocyclohexenepropionates 2 with (R)-phenylglycinol, the stereoselective ...
Bosch Cartes, Joan, Amat Tusón, Mercedes, Griera Farres, Rosa, Fabregat, Robert   +3 more
core   +1 more source

Synthesis of Poly(1,4‐anthraquinone) Using Catalytic Amounts of Nickel

Advanced Science
Multivalent metal batteries are attractive options to diversify energy storage options offering higher sustainability, but the high charge density of multivalent ions poses challenges to electrode materials.
Florin Adler, Sebastián Pinto‐Bautista, Christoph Lorenz, Lars Hinrichs, Marcel Weil, Birgit Esser   +5 more
doaj   +1 more source

Integrated CO2 capture and conversion into methanol units: Assessing techno-economic and environmental aspects compared to CO2 into SNG alternative

Journal of CO2 Utilization
Using carbon dioxide (CO2) as a raw-material to produce value-added chemicals has a strategic role to play in the decarbonization of energy resources and the transition to a climate-neutral economy.
Rania Djettene, Lionel Dubois, Marie-Eve Duprez, Guy De Weireld, Diane Thomas   +4 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source