Results 61 to 70 of about 175,975,280 (226)
Nature Communications, 2023 Modern cells are complex chemical compartments tightly regulated by an underlying DNA-encoded program. Achieving a form of coupling between molecular content, chemical reactions, and chassis in synthetic compartments represents a key step to the assembly
Tommaso P. Fraccia, Nicolas Martin
doaj +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Synthetic route and chemical structure of heparin-poloxamer (HP) conjugate.
, 2013 (A: Synthetic route of amine-terminated poloxamer 407; B: Chemical structure of HP conjugate).
Ho Lun Wong (450683) +11 more
core +1 more source
Медицинская иммунологияSynthetic peptides provide a promising basis for HIV vaccine development. Following their administration, the immune response is focused only on a specific epitope. Moreover, they are able to activate both humoral and cellular pathways of immune response,
S. V. Korobova +4 more
doaj +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Synthetic route for the tripeptide peptidomimetics.
, 2015 Synthetic route for the tripeptide peptidomimetics.
Stephanie Tay (777269) +6 more
core +1 more source
Macromolecular Rapid CommunicationsABSTRACT Polysarcosine (pSar) is an attractive alternative to poly(ethylene glycol) for a broad range of bioapplications. However, the preparation of high‐molecular‐weight pSar remains limited by challenges associated with the synthesis and purity of sarcosine N‐carboxyanhydride (Sar‐NCA).
Anna Golunova +6 more
openaire +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Synthetic route to studied ion-exchange resins.
, 2015 Synthetic route to studied ion-exchange resins.
Maciej Zalas (735524) +2 more
core +1 more source