Results 81 to 90 of about 175,975,280 (226)

Preparation of some organotin polymers via new synthetic route

, 1999
Aims to prepare some organotin polymers based on N‐substituted acrylamide and methylacrylamide acid esters via a new synthetic route. Tri‐n‐butyltin‐∝‐bromoacrylate monomer (TBTBA) was prepared and polymerisation carried out.
Mohamed A. Radwan
core   +1 more source

Evacuation path optimization algorithm for grassland fires based on SAR imagery and intelligent optimization

Frontiers in Environmental Science
The acceleration of urbanization and the impact of climate change have led to an increasing frequency and intensity of grassland fires, posing severe challenges to resident safety and ecological protection.
Ziyang Zhang, Lingye Tan, Robert L. K. Tiong   +2 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Synthetic route to obtain L-homoserine lactone hydrochloride.

, 2019
Synthetic route to obtain L-homoserine lactone hydrochloride.
Jessica Foster (6397079), Iryna V. Kosakivska (6397082), Geert Potters (446254), Olga S. Iungin (6397076), Lidia M. Babenko (6397070), Andrew J. Spiers (77864), Olena V. Moshynets (6397067), Sergiy P. Rogalsky (6397073)   +7 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Degradation of Synthetic-Based Drilling Mud Base Fluids by Gulf of Mexico Sediments: Final Report [PDF]

, 2006
Report on a predictor model that determines the degradation rate of Synthetic-based fluids (SBF) from deep-sea drilling and assesses the impact of SBFs on the sediment microbial ecology in the Gulf of ...
Roberts, Deborah J., Nguyen, Alan H.
core  

Data-Driven Approach for Passenger Assignment in Urban Rail Transit Networks: Insights From Passenger Route Choices and Itinerary Choices

Journal of Advanced Transportation
Congestion in urban rail transit (URT) systems often results in passengers being left behind on platforms due to trains’ reaching capacity. Distinguishing between the travel choice behaviors of passengers who board the first arriving train (Type I ...
Di Wen, Hongxia Lv, Hao Yu
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Synthetic route to obtain N-hexanoyl-L-homoserine lactone.

, 2019
Synthetic route to obtain N-hexanoyl-L-homoserine lactone.
Jessica Foster (6397079), Iryna V. Kosakivska (6397082), Geert Potters (446254), Olga S. Iungin (6397076), Lidia M. Babenko (6397070), Andrew J. Spiers (77864), Olena V. Moshynets (6397067), Sergiy P. Rogalsky (6397073)   +7 more
core   +1 more source