Results 41 to 50 of about 166,294,980 (268)

Responses of Medicinal and Aromatic Plants to Engineered Nanoparticles

Applied Sciences, 2021
Medicinal and aromatic plants have been used by mankind since ancient times. This is primarily due to their healing effects associated with their specific secondary metabolites (some of which are also used as drugs in modern medicine), or their ...
Katarina Kralova, Josef Jampilek
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Synthetic route of FP2

, 2016
Synthetic route of ...
Wei Li (7081), Xiao Duan (3129429), Lin Zhu (192179), Li Fan (170266), Tiehong Yang (288458), Hong Wu (105254), Youbei Qiao (434012)   +6 more
core   +1 more source

Electrochemistry of Inorganic OCT-PbS/HDA and OCT-PbS Photosensitizers Thermalized from Bis(N-diisopropyl-N-octyldithiocarbamato) Pb(II) Molecular Precursors

Molecules, 2020
Inorganic nanocrystal solar cells have been tagged as the next generation of synthesizers that have the potential to break new ground in photovoltaic cells.
Mojeed A. Agoro, Johannes Z. Mbese, Edson L. Meyer   +2 more
doaj   +1 more source

Non-enzymatic oligonucleotide ligation in coacervate protocells sustains compartment-content coupling

Nature Communications, 2023
Modern cells are complex chemical compartments tightly regulated by an underlying DNA-encoded program. Achieving a form of coupling between molecular content, chemical reactions, and chassis in synthetic compartments represents a key step to the assembly
Tommaso P. Fraccia, Nicolas Martin
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Immunogenic properties of synthetic peptides copying the V3 loop of HIV-1 gp120 envelope protein: effects of various administration routes and poly(I:C) immunoadjvant use

Медицинская иммунология
Synthetic peptides provide a promising basis for HIV vaccine development. Following their administration, the immune response is focused only on a specific epitope. Moreover, they are able to activate both humoral and cellular pathways of immune response,
S. V. Korobova, V. A. Toporova, B. I. Alkhazova, M. E. Golovina, P. G. Aparin   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source