Results 31 to 40 of about 166,294,980 (268)
Application and Suitability of Polymeric Materials as Insulators in Electrical Equipment
In this paper, the applications of thermoplastic, thermoset polymers, and a brief description of the functions of each subsystem are reviewed. The synthetic route and characteristics of polymeric materials are presented.
SK Manirul Haque +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Novel, functional materials based on chitin of marine origin and lignin were prepared. The synthesized materials were subjected to physicochemical, dispersive-morphological and electrokinetic analysis.
Marcin Wysokowski +8 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Microwave synthesis of B4C nanopowder for subsequent spark plasma sintering
Utilization of microwave-assisted (MW) synthesis and subsequent spark plasma sintering as an efficient and rapid synthetic route toward the preparation and consolidation of ultrahard B4C boron carbide without additives is reported. Magnesium dodecaboride
D. Davtyan +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Method for Fast, High-Precision Characterization of Synthetic Biology Devices [PDF]
Engineering biological systems with predictable behavior is a foundational goal of synthetic biology. To accomplish this, it is important to accurately characterize the behavior of biological devices.
Weiss, Ron +4 more
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Rule-Based Design of Synthetic Transcription Factors in Eukaryotes
To design and build living systems, synthetic biologists have at their disposal an increasingly large library of naturally derived and synthetic parts.
Peccoud, Jean +2 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Impact resistance of concrete using dovetailed fibres and type 2 synthetic fibres [PDF]
This paper investigates the relative performance of new dovetailed (DT) cross section fibres with regard to impact resistance and energy absorption of concrete.
Richardson, Alan, Batey, David
core

