Results 21 to 30 of about 166,294,980 (268)

Cumulative complexity meta-metrics as an efficiency measure and predictor of PMI during synthetic route design [PDF]

, 2023
Functioning as a surrogate for step count, a cumulative complexity meta-metric, calculated along the longest linear sequence of a synthetic route, is demonstrated to be a useful predictor of process mass intensity (PMI).
Brian, Taylor, George, Karageorgis, Gareth, Howell, Charlotte, Coomber, Lucrezia, Angelini   +4 more
core   +2 more sources

Methodological Experience in the Teaching-Learning of the English Language for Students with Visual Impairment

Education Sciences, 2021
This document evidences an innovative methodological vision in the teaching-learning process of the English language focused on the inclusion of all its students in a heterogeneous learning environment. Learning a foreign language as a second language is
Jorge Cárdenas, Esteban Inga
doaj   +1 more source

Cost of Goods Analysis Facilitates an Integrated Approach to Identifying Alternative Synthesis Methodologies for Lower Cost Manufacturing of the COVID-19 Antiviral Molnupiravir [version 1; peer review: 2 approved]

Gates Open Research, 2022
Orally delivered drugs offer significant benefits in the fight against viral infections, and cost-effective production is critical to their impact on pandemic response in low- and middle-income countries.
Christopher Peterson, Anita Deshpande, Sayan Paria, Andrew Harmon, Saeed Ahmad, Trevor Laird, John Dillon   +6 more
doaj   +1 more source

Ketone Formation via Decarboxylation Reactions of Fatty Acids Using Solid Hydroxide/Oxide Catalysts

Inorganics, 2018
A sustainable route to ketones is described where stearone is produced via ketonic decarboxylation of stearic acid mediated by solid base catalysts in yields of up to 97%, at 250 °C.
Benjamin Smith, Li Li, Diego D. Perera-Solis, Louise F. Gildea, Vladimir L. Zholobenko, Philip W. Dyer, H. Christopher Greenwell   +6 more
doaj   +1 more source

Sorbents based on the manganese oxides designed for selective removal of lithium ions

Хімія, фізика та технологія поверхні
Two manganese oxide-based adsorbents were synthesized using a precipitation method followed by hydrothermal treatment of reagents. The templating method was employed to create the sorbents’ selectivity, ensuring efficient extraction of lithium ions from
L. Y. Kotynska, M. Holdynsky, O. S. Fedoryshin, O. I. Zakutevsky, I. V. Romanova   +4 more
doaj   +1 more source

Removal of cesium and strontium ions from aqueous solutions using metakaolin based geopolymers

Хімія, фізика та технологія поверхні
The aim of presented work was to synthesize geopolymers based on the metakaolin and to determine their adsorption capability in the process of cesium and strontium ions removal from the aqueous solutions.
D. V. Tarnovsky, O. S. Fedoryshyn, O. A. Vyshnevskyi, I. V. Romanova   +3 more
doaj   +1 more source

Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model

Molecules, 2020
Zebrafish (Danio rerio) larvae have gained attention as a valid model to study in vivo drug metabolism and to predict human metabolism. The microinjection of compounds, oligonucleotides, or pathogens into zebrafish embryos at an early developmental stage
Yu Mi Park, Markus R. Meyer, Rolf Müller, Jennifer Herrmann   +3 more
doaj   +1 more source

Oral Cell-Targeted Delivery Systems Constructed of Edible Materials: Advantages and Challenges

Molecules, 2022
Cell-targeted delivery is an advanced strategy which can effectively solve health problems. However, the presence of synthetic materials in delivery systems may trigger side effects.
Xiaolong Li, Zihao Wei, Changhu Xue
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Synthetic Cathinone Impact on the Protein Profile of Intestinal Caco-2 Cells

Chemistry Proceedings
The global rise in New Psychoactive Substances (NPS), particularly synthetic cathinones, poses significant public health concerns due to their association with toxicity and fatalities.
Mariana Meneses, Helena Gaspar, Rita Pacheco   +2 more
doaj   +1 more source