Results 21 to 30 of about 284,250 (248)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Impact-induced Contamination of Ganymede’s Deep Ice Shell
Juno flew by Ganymede in 2021 June and measured the microwave brightness temperatures of the ice shell at six frequencies from 0.6–22 GHz. Based on the increasing brightness temperature with wavelength, S. Brown et al.
Yu Yu Phua, David J. Stevenson
doaj +1 more source
Modeling the Formation of Selk Impact Crater on Titan: Implications for Dragonfly
Selk crater is an ∼80 km diameter impact crater on the Saturnian icy satellite Titan. Melt pools associated with impact craters like Selk provide environments where liquid water and organics can mix and produce biomolecules like amino acids. It is partly
Shigeru Wakita +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Distribution of Impactor Core Material During Large Impacts on Earth-like Planets
Large impacts onto young rocky planets may transform their compositions, creating highly reducing conditions at their surfaces and reintroducing highly siderophile metals to their mantles.
Jonathan P. Itcovitz +4 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Telescope-to-Fireball Characterization of Earth Impactor 2022 WJ1
Comparing how an asteroid appears in space to its ablation behavior during atmospheric passage and finally to the properties of associated meteorites represents the ultimate probe of small near-Earth objects.
Theodore Kareta +12 more
doaj +1 more source
Investigation of Different Cardboard Materials Under Impact Loads
Packaging materials, such as cardboard, must endure vigorous loads during handling and transport, which could lead to damage to the packaged goods. To ensure that the transported goods reach the consumer safely, a profound knowledge of the behavior of ...
Philipp Johst +4 more
doaj +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Asteroids pose potential hazards to Earth. The recent NASA Double Asteroid Redirection Test mission successfully demonstrated the change of an asteroid’s orbit by a kinetic impactor.
Kaiyi Dai +6 more
doaj +1 more source

