The Nadir Crater offshore West Africa: A candidate Cretaceous-Paleogene impact structure. [PDF]
Sci Adv, 2022 Nicholson U +3 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Serotype-Specific Sugars Impact Structure but Not Functions of the Trimeric Autotransporter Adhesin EmaA of Aggregatibacter actinomycetemcomitans. [PDF]
J Bacteriol, 2022 Tang-Siegel GG +3 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Experimental Study on the Performance of Polyurethane-Steel Sandwich Structure under Debris Flow
Applied Sciences, 2017 Polyurethane-steel sandwich structure, which creatively uses the polyurethane-steel sandwich composite as a structural material, is proposed to strengthen the impact resistance of buildings under debris flow.
Peizhen Li, Shutong Liu, Zheng Lu
doaj +1 more source
Globally distributed iridium layer preserved within the Chicxulub impact structure. [PDF]
Sci Adv, 2021 Goderis S +32 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Surface damage mitigation of titanium and its alloys via thermal oxidation: A brief review
Reviews on Advanced Materials Science, 2019 Titanium (Ti) and its alloys have been extensively applied in various fields of chemical industry, marine, aerospace and biomedical devices because of a specific combination of properties such as high strength to weight ratio, exceptional corrosion ...
Lin Naiming +15 more
doaj +1 more source
The Boltysh impact structure: An early Danian impact event during recovery from the K-Pg mass extinction. [PDF]
Sci Adv, 2021 Pickersgill AE +4 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source