Results 121 to 130 of about 16,071,507 (300)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Analysis of financial opportunities [PDF]

open access: yesИкономика и компютърни науки, 2018
We will start with an analysis structure that defines the key areas in which long-term funding sources will be analyzed and attracted. We will then look at the techniques for calculating the impact on the company's financial performance caused by the ...
Dessislava Kostova – Pickett
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

IMPACT: Health and Welfare Division: report 2002-2003.

open access: yes, 2003
The Government published its ten-year health strategy, Quality and fairness: A health system for you, in November 2001. It contained ambitious targets to improve services and reduce inequalities with far-reaching proposals on everything from bed ...
IMPACT
core  

Fostering Impactful Careers: A Tool for Reflection

open access: yes
Our EUR strategic priorities of Creating Positive Societal Impact and Recognition & Rewards mean that we increasingly support those who are passionate about creating and fostering positive societal impact.
Evaluating Societal Impact
core   +1 more source

CGIAR GENDER Impact Platform Newsletter, issue 2, June-July 2022

open access: yes, 2023
In this issue, we share with you latest news from the CGIAR GENDER Impact Platform as well as updates on gender research from across CGIAR's research portfolio.
CGIAR GENDER Impact Platform
core   +1 more source

Unveiling the armor: experimental study on ballistic impact resistance of silica aerogel, sorbothane, and graphite sandwich composites

open access: yesDiscover Materials
Ballistic armour is intended to save lives by absorbing the impact of bullets and preventing them from entering the wearer’s body. Especially for police enforcement, security, and military professionals.
S. L. Pradeep Kumar   +5 more
doaj   +1 more source

Study on the Energy Absorption Characteristics of Different Composite Honeycomb Sandwich Structures under Impact Energy

open access: yesApplied Sciences
A honeycomb structure is a sandwich structure widely used in fuselage, among which the hexagonal honeycomb core is the most widely used. The energy absorption characteristics and impedance ability of the structure are the main reasons that directly ...
Bianhong Chang   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Research Progress on Composite Structure of Warships in Impact Protection

open access: yes水下无人系统学报
As modern naval battles become increasingly complex, the structural protection of warships has become the key to enhancing survivability and combat effectiveness.
Tao ZHANG   +3 more
doaj   +1 more source

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