Results 181 to 190 of about 25,604,119 (393)

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

A compilation of information and data on the Manson impact structure [PDF]

open access: yes
A problem for the impact hypothesis for the Cretaceous-Tertiary (K-T) mass extinction is the apparent absence of an identifiable impact site. The Manson Impact Structure is a candidate because it is the largest recognized in the U.S.; it is relatively ...
Anderson, Raymond R., Hartung, Jack B.
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

The Impact of Income and Family Structure on Delinquency [PDF]

open access: yes
There is no more important issue in the economics of the family than the impact of parents on the behavior of their children. By providing rewards and imposing constraints, parents seek to affect their children’s behavior.
Llad Phillips, William S. Comanor
core  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Capital structure in South Korea: A Quantile Regression Approach [PDF]

open access: yes
This paper analyzes capital structure in South Korea from 1991 until 1999. The paper makes use of quantile regression methods to explore the changing distribution of debt-capital ratios across firms and over time.
Fattouh, Bassam   +2 more
core  

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