Results 191 to 200 of about 25,605,949 (420)

Differential functional organization of amygdala-medial prefrontal cortex networks in macaque and human

open access: yesCommunications Biology
Over the course of evolution, the amygdala (AMG) and medial frontal cortex (mPFC) network, involved in behavioral adaptation, underwent structural changes in the old-world monkey and human lineages.
Camille Giacometti   +8 more
doaj   +1 more source

Polymer Matrix Sand Composites for Enhanced Ballistic Impact Resistance [PDF]

open access: yesarXiv
With the ever-increasing threat of ballistic impact, it is crucial to provide a solution that is not only effective but also economical. A majority of studies contribute toward alternatives to monolithic structures by incorporating sandwiched cores, which are often prone to crushing and delamination.
arxiv  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Spillover and crossover effects of exposure to work‐related aggression and adversities: A dyadic diary study

open access: yesAggressive Behavior, Volume 49, Issue 1, Page 85-95, January 2023., 2023
Abstract The past two decades have produced extensive evidence on the manifold and severe outcomes for victims of aggression exposure in the workplace. However, due to the dominating individual‐centered approach, most findings miss a social network perspective.
Alexander Herrmann   +2 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Semi‐supervised classification of fundus images combined with CNN and GCN

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Diabetic retinopathy (DR) is one of the most serious complications of diabetes, which is a kind of fundus lesion with specific changes. Early diagnosis of DR can effectively reduce the visual damage caused by DR. Due to the variety and different morphology of DR lesions, automatic classification of fundus images in mass screening can ...
Sixu Duan   +8 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

AAPM Task Group 298: Recommendations on certificate program/alternative pathway candidate education and training

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Entry into the field of clinical medical physics is most commonly accomplished through the completion of a Commission on Accreditation of Medical Physics Educational Programs (CAMPEP)‐accredited graduate and residency program. To allow a mechanism to bring valuable expertise from other disciplines into clinical practice in medical physics, an “
Joann I. Prisciandaro   +6 more
wiley   +1 more source

Shatter cones in Illinois: Evidence for metoeritic impacts at Glasford and Des Plaines [PDF]

open access: yes
Shatter cone fragments were recovered from rock cores at two previously suspected, but heretofore unverified, impact structures in Illinois. Both sites are buried features known from geophysical surveys and drill holes.
Mchone, John F.   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy