Results 101 to 110 of about 1,370,091 (259)

Importance of OGTT for diagnosis of Diabetes in thalassemia major patients

مجله دانشگاه علوم پزشکی گرگان, 2008
Background and Objective: Thalassemia major is a genetic disorder. Blood transfusion is critical for survival in these patients. Over the course of the past two and three decade’s hyper transfusion therapy in these patients has increased significant ...
Farzad Najafipour (MD), Roohangiz Sari Sorkhabi (MD), Navideh Haji Aghai (GP), Masoomeh Zareizadeh (MD), Amir Bahrami (MD)   +4 more
doaj  

Prevalence of Obesity and its Relationship with the Presence of Type 2 Diabetes [PDF]

Applied Medical Informatics, 2011
Aim: The aim of the present article was to identify the prevalence of obesity and to evaluate the relationship between body mass index, waist circumference and fasting plasma glucose in a sample of Romanian patients from general population.
Lucreţia PÎRCĂLĂBOIU
doaj  

Men: baseline characteristics and the onset of impaired fasting glucose^* according to fasting plasma glucose levels.

, 2014
Values are expressed as mean ± standard deviation.Quartile 1: fasting plasma glucose
Bunzo Matsuura (429489), Mitsuhito Koizumi (442547), Yasuhiko Todo (631862), Shin Yamamoto (631863), Shinya Furukawa (631860), Keitarou Kawasaki (631861), Yoichi Hiasa (156596), Teruki Miyake (631859), Teru Kumagi (43326), Masanori Abe (421879), Masashi Hirooka (429488), Kohichiro Kitai (631864)   +11 more
core   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Relationship between interoceptive sensitivity and impaired fasting glucose in early pregnancy

Huli yanjiu
ObjectiveTo explore the relationship between interoceptive sensitivity and impaired fasting glucose(IFG) in early pregnancy.MethodsA cross⁃sectional study method was conducted.A total of 233 pregnant women who established their prenatal records in the ...
LIU Bin, TIAN Qianqian, TAN Xiaohan, LIU Jun, DING Minhua, WANG Xiaohua, ZHANG Wei   +6 more
doaj  

Best-Fitting Multivariate Multinomial Logistic Regression Model Predicting Year 3 Glucose Group (Normal, Impaired Fasting Glucose, Diabetes Mellitus).

, 2014
Reference group  =  normal Year 3 glycemic status.IFG  =  impaired fasting glucose.
Megan E. Piper (173990), Wei-Yin Loh (571915), Stevens S. Smith (571914), Michael C. Fiore (173996), James H. Stein (166200), Asha Asthana (405593), Timothy B. Baker (173994)   +6 more
core   +1 more source

Quantifying the improvement of surrogate indices of hepatic insulin resistance using complex measurement techniques [PDF]

, 2012
We evaluated the ability of simple and complex surrogate-indices to identify individuals from an overweight/obese cohort with hepatic insulin-resistance (HEP-IR).
Martin Osterhoff, Osterhoff Martin, Pfeiffer, Andreas F. H., Christian V Loeffelholz, Roden, Michael, Dr., Loeffelholz Christian v., Pfeiffer Andreas F. H., Nowotny, Peter, Möhlig Matthias, Nowotny Peter, Khan, Michael, Hattersley, John G., Weickert Martin O., Hierholzer, Johannes, Martin O Weickert, Arafat Ayman M., Roden Michael, Arafat, Ayman M., Machann Jürgen, Peter Nowotny, Weickert, Martin O., Möhlig, Matthias, Loeffelholz, Christian von, Hattersley John G., Michael Khan, Johannes Hierholzer, John G Hattersley, Matthias Möhlig, Michael Roden, Osterhoff, Martin, Khan Michael, Andreas F H Pfeiffer, Ayman M Arafat, Hierholzer Johannes, Jürgen Machann, Machann, Jürgen   +35 more
core   +2 more sources

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

Advanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan, Yijie Qiu, Yan Zhu, Quan Wang, Jiangtao Lin, Yourong Duan, Qi Wang, Yi Dong   +7 more
wiley   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source