Results 231 to 240 of about 1,571,048 (334)

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Association between hepatic steatosis index and impaired fasting glucose: a multicenter retrospective cohort study in China. [PDF]

Front Endocrinol (Lausanne)
Chen Y, Han J, Zhao S, Shi Y, Jia H, Lu S, Wu J, Huang S.   +7 more
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

A cross-sectional study on the association between major dietary pattern and impaired fasting glucose. [PDF]

Front Nutr
Shojaei-Zarghani S, Fattahi MR, Kazemi A, Najafi N, Safarpour AR.   +4 more
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Educational and economic disparities and risk factors associated with diabetes and impaired fasting glucose in Cambodia: analysis of a national population-based study. [PDF]

J Glob Health
Haruyama R, Rahman MS, Rahman MM, Khim SA, Moadsiri A, Chham S, Chhim S, Kol H, Phy M.   +8 more
europepmc   +1 more source

Prevalence of Diabetes and Impaired Fasting Glucose in Adults in the U.S. Population

Diabetes Care, 2006
C. Cowie, Keith F. Rust, D. Byrd-Holt, M. Eberhardt, K. Flegal, M. Engelgau, S. Saydah, Desmond E. M. Williams, L. Geiss, E. Gregg   +9 more
semanticscholar   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Association between the aspartate aminotransferase-to-alanine aminotransferase ratio and the reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study. [PDF]

Front Endocrinol (Lausanne)
Zhang K, Chen L, Deng Z, Rong R, Xu L, Xu L, Zeng S, Hu H.   +7 more
europepmc   +1 more source

Impaired fasting glucose and impaired glucose tolerance have distinct lipoprotein and apolipoprotein changes: the insulin resistance atherosclerosis study.

Journal of Clinical Endocrinology and Metabolism, 2013
C. Lorenzo, Sara Hartnett, A. Hanley, M. Rewers, L. Wagenknecht, A. Karter, S. Haffner   +6 more
semanticscholar   +1 more source