Results 111 to 120 of about 1,961,883 (258)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
آداب الكوفةSperber & Wilson (2005:468) see Pragmatics as is " the study of how contextual factors interact with linguistic meaning in the interpretation of utterances". Doctors often recognize patterns in people’s speech from their utterances.
طالب علي, حسن الكعبي
doaj +1 more source
Short-term and working memory in children with specific language impairment [PDF]
, 2006 Investigations of the cognitive processes underlying Specific Language Impairment (SLI) have implicated deficits in the storage and processing of phonological or verbal information.
Archibald, Lisa M. D.
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Screwing With Our Embodiment: A Response to Thorneycroft’s Re-Imagining of the Social Model
Scandinavian Journal of Disability ResearchThis paper presents a response to Thorneycroft’s (2024) proposed conceptual solution to the disability-impairment binary at the heart of the social model of disability, also published in this journal.
Brian Watermeyer, Clare Harvey
doaj +1 more source
Global estimates on the number of people blind or visually impaired by Uncorrected Refractive Error: a meta-analysis from 2000 to 2020 [PDF]
Background: Uncorrected refractive error (URE) is a readily treatable cause of visual impairment (VI). This study provides updated estimates of global and regional vision loss due to URE, presenting temporal change for VISION 2020 Methods: Data from ...
Vision Loss Expert Group of the Global Burden of Disease Study, +5 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Teuken Bidikay, Revista Latinoamericana de Investigación en Organizaciones Ambiente y Sociedad, 2015 El presente trabajo constituye una aproximación teórica al tema de deterioro del valor de propiedad planta y equipo. Inicialmente, se realiza un referente teórico, el cual comienza con la identificación del concepto a partir de la norma y del trabajo de ...
Sandra Patricia Perea Murillo
doaj
Brain Impairment in Indigenous Populations
, 2019 This special issue on brain impairment in Indigenous populations represents a significant advancement in the field. The contributions will help us understand the causes of brain injury in Indigenous communities, the impacts and the development of ...
Cullen, Jennifer +2 more
core +1 more source