Results 101 to 110 of about 1,760,363 (317)

As informações sobre o impairment test nas empresas brasileiras que negociam ADR’S na bolsa de valores dos Estados Unidos: uma verificação nas demonstrações financeiras padronizadas (CVM) e no relatório 20F (SEC) [PDF]

, 2007
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisO presente trabalho trata-se da realização do impairment test no ativo imobilizado da empresa.
Souza, Maíra Melo de
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Mild Cognitive Impairment [PDF]

New England Journal of Medicine, 2004
As individuals age, the quality of cognitive function becomes an increasingly important topic. The concept of mild cognitive impairment (MCI) has evolved over the past 2 decades to represent a state of cognitive function between that seen in normal aging and dementia.
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Global estimates on the number of people blind or visually impaired by age-related macular degeneration: a meta-analysis from 2000 to 2020 [PDF]

Background: We aimed to update estimates of global vision loss due to age-related macular degeneration (AMD). Methods: We did a systematic review and meta-analysis of population-based surveys of eye diseases from January, 1980, to October, 2018.
Vision Loss Expert Group of the Global Burden of Disease Study,, GBD 2019 Blindness and Vision Impairment Collaborators,, Vision Loss Expert Group of the Global Burden of Disease Study, GBD 2019 Blindness and Vision Impairment Collaborators   +3 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Short-term and working memory in children with specific language impairment [PDF]

, 2006
Investigations of the cognitive processes underlying Specific Language Impairment (SLI) have implicated deficits in the storage and processing of phonological or verbal information.
Archibald, Lisa M. D.
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Using support vector machines with multiple indices of diffusion for automated classification of mild cognitive impairment

, 2012
Few studies have looked at the potential of using diffusion tensor imaging (DTI) in conjunction with machine learning algorithms in order to automate the classification of healthy older subjects and subjects with mild cognitive impairment (MCI).
Lamberton, Franck, David Prvulovic, O’Neill, Desmond, Desmond O'Neill, Harald Hampel, Prvulovic David, Bartley, M., Prvulovic, D., Coughlan, T., Mazoyer, B., Lamberton, F., Collins, D.R., Bokde, Arun L W, Laurence O'Dwyer, Coughlan Tara, O'Neill, Desmond, Ewers, Michael, Bokde, A.L., O'Neill, D., Ewers, M., Mazoyer Bernard, Franck Lamberton, Collins, D. Rónán, O'Neill Desmond, Arun L W Bokde, Tara Coughlan, Bartley, Máiréad, Bokde Arun L. W., Faluyi, Y.O., Hampel Harald, D Rónán Collins, O'Dwyer Laurence, O'Dwyer, Laurence, Collins, D Rónán, Máiréad Bartley, Tanner, C., Faluyi, Yetunde O., Tanner Colby, Bartley Máiréad, O’Dwyer, Laurence, Bokde, Arun L. W., Lamberton Franck, Faluyi Yetunde O., Mazoyer, Bernard M., Mazoyer, Bernard, Hampel, Harald, Prvulovic, David, Michael Ewers, O'Dwyer, L.G., Faluyi, Yetunde O, Colby Tanner, Collins D. Rónán, Tanner, Colby, Hampel, H., Coughlan, Tara, Ewers Michael, Yetunde O Faluyi, Bernard Mazoyer   +57 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Disclosure Requirements in IAS 36 Paragraph 134. A Study of Company Characteristics Explaining Swedish Companies' Compliance with Disclosure Requirements on Goodwill Impairment Testing [PDF]

, 2013
Background and Discussion: The adoption of the IFRS by Swedish companies was an arduous task which required a lot of resources and time. The regulations that the IFRS contain are more complex and require more extensive disclosures than Swedish companies ...
Oksana, Henriksson, Fallström, Lyubov
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