Results 81 to 90 of about 1,760,363 (317)

Are language and social communication intact in children with congenital visual impairment at school age? [PDF]

open access: yes, 2009
Background:  Development of children with congenital visual impairment (VI) has been associated with vulnerable socio-communicative outcomes often bearing striking similarities to those of sighted children with autism.1 To date, very little is known ...
Dale, Naomi   +9 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Severity of specific language impairment predicts delayed development in number skills

open access: yes, 2013
The extent to which mathematical development is dependent upon language is controversial. This longitudinal study investigates the role of language ability in children's development of number skills.
Kevin eDurkin   +8 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Lexicality and frequency in specific language impairment: accuracy and error data from two nonword repetition tests [PDF]

open access: yes, 2010
Purpose: Deficits in phonological working memory and deficits in phonological processing have both been considered potential explanatory factors in Specific Language Impairment (SLI).
Pine, JM   +14 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Analyses of Physical and Physiological Responses during Competition in Para-Footballers with Cerebral Palsy: A Systematic Review

open access: yesApplied Sciences
Background: Classification of athletes in cerebral palsy (CP) football is a key action that aims to promote the participation of all players by minimizing the impact of their physical disabilities on the outcome of the competition by establishing sports ...
Santiago Álvarez-Hernández   +5 more
doaj   +1 more source

Functional Impairment, Marital Quality, and Their Effects on Marital Dissolution [PDF]

open access: yes, 2016
Numerous studies show evidence that personal health affects marital relationships, and therefore, marital dissolution. However, little work examines the effects of functional impairment on marital dissolution.
Fuhrman, Meaghan
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Longitudinal patterns of behavioral, emotional, and social difficulties and self-concept in adolescents with a history of specific language impairment [PDF]

open access: yes, 2012
Purpose: This study explored the prevalence and stability of behavioral difficulties and self-concepts between 8 and 17 years in a sample of children with a history of specific language impairment (SLI).
Dockrell, Julie E.   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy