Results 81 to 90 of about 1,961,883 (258)

Studying Disability: A Multi-Stakeholder Perspective on Requesting Accommodation in Higher Education

open access: yesSocial Sciences
Including students with disabilities in higher education is a global political objective and is considered a human right. However, many students do not feel included and hesitate to ask for the help they need to succeed in their education.
Tone Ristad   +4 more
doaj   +1 more source

Using support vector machines with multiple indices of diffusion for automated classification of mild cognitive impairment [PDF]

open access: yes, 2012
Few studies have looked at the potential of using diffusion tensor imaging (DTI) in conjunction with machine learning algorithms in order to automate the classification of healthy older subjects and subjects with mild cognitive impairment (MCI).
Lamberton, Franck   +57 more
core   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Functional impairment in South African children and adolescents with obsessive-compulsive disorder [PDF]

open access: yes, 2009
Includes bibliographical references (leaves 109-115).This research aimed to increase current understanding of functional impairment in children and adolescents with Obsessive-Compulsive Disorder (OCD).
Hoppe, Lara Judy
core   +1 more source

Perceived Stigmatization of Children with Speech-Language Impairment and Their Parents [PDF]

open access: yes, 2008
Objective: Developmental disorders in childhood are generally assumed to have stigmatizing effects. The goal of the present study was to assess whether parents of children with speech-language impairment perceive stigmatization of their child or ...
Macharey, Georg   +1 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Functional Impairment, Marital Quality, and Their Effects on Marital Dissolution [PDF]

open access: yes, 2016
Numerous studies show evidence that personal health affects marital relationships, and therefore, marital dissolution. However, little work examines the effects of functional impairment on marital dissolution.
Fuhrman, Meaghan
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Development of a pictorial scale for assessing functional interference with chronic pain: the Pictorial Pain Interference Questionnaire

open access: yesJournal of Pain Research, 2018
Andrew J Cook,1 David A Roberts,2 Karen C Nelson,3 Brian R Clark,4 B Eugene Parker Jr4 1Department of Psychiatry and Behavioral Science, Texas A&M Health Science Center College of Medicine, Temple, TX, USA; 2Epiceutical Labs, Charlottesville, VA, USA;
Cook AJ   +4 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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