Results 61 to 70 of about 575,905 (318)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

A proposed benchmark model using a modularised approach to calculate IFRS 9 expected credit loss

Cogent Economics & Finance, 2020
The objective of this paper is to develop a methodology to calculate expected credit loss (ECL) using a transparent-modularised approach utilising three components: probability of default (PD), loss given default (LGD) and exposure at default (EAD).
Willem Daniel Schutte, Tanja Verster, Derek Doody, Helgard Raubenheimer, Peet Jacobus Coetzee   +4 more
doaj   +1 more source

Visuoconstructional Impairment in Subtypes of Mild Cognitive Impairment [PDF]

Applied Neuropsychology: Adult, 2015
Clock Drawing Test performance was examined alongside other neuropsychological tests in mild cognitive impairment (MCI). We tested the hypothesis that clock-drawing errors are related to executive impairment. The current research examined 86 patients with MCI for whom, in prior research, cluster analysis was used to sort patients into dysexecutive ...
Ahmed, Samrah, Brennan, Laura, Eppig, Joel, Price, Catherine C, Lamar, Melissa, Delano-Wood, Lisa, Bangen, Katherine J, Edmonds, Emily C, Clark, Lindsey, Nation, Daniel A, Jak, Amy, Au, Rhoda, Swenson, Rodney, Bondi, Mark W, Libon, David J   +14 more
openaire   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Biennial Report of the Texas Correctional Office on Offenders with Medical and Mental Impairments [PDF]

, 2013
This report complies with state legislation addressing all aspects of the criminal justice ...
Texas Correctional Office on Offenders with Medical and Mental Impairments
core  

Impairment‐aware resource allocation scheme for elastic optical networks with different service priorities

IET Communications
Today, elastic optical networks (EONs) are required to accommodate traffic with different service priorities. For example, mission‐critical applications such as industrial internet, smart grids, and remote surgery require an ultra‐reliable low‐latency ...
Kusala Munasinghe, Nishan Dharmaweera, Chamitha de Alwis, Uditha Wijewardhana, Rajendran Parthiban   +4 more
doaj   +1 more source

An impairment in sniffing contributes to the olfactory impairment in Parkinson's disease [PDF]

Proceedings of the National Academy of Sciences, 2001
Although the presence of an olfactory impairment in Parkinson's disease (PD) has been recognized for 25 years, its cause remains unclear. Here we suggest a contributing factor to this impairment, namely, that PD impairs active sniffing of odorants. We tested 10 men and 10 women with clinically typical PD, and 20 age- and gender-matched
Stappen, Iris, Sobel, N., Thomason, Moriah, Tanner, Caroline M., Gabrieli, J.D.E., Bower, James M, Sullivan, Edith V., Tetrud, James W.   +7 more
openaire   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Impairments on "open-ended" executive function tests in autism [PDF]

, 2009
The executive function (EF) theory of autism has received much support recently from a growing number of studies. However, executive impairments have not always been easy to identify consistently and so novel "ecologically valid" tests have been designed
Burgess, P. W., Sarah J. White, White, S. J., Hill, Elisabeth L., Paul W. Burgess, Elisabeth L. Hill   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source