Results 81 to 90 of about 575,905 (318)

73th Legislature of Texas

, 1993
Biennial report of the Texas Council on Offenders with Mental Impairments describing goals, activities, and ...
Texas Council on Offenders with Mental Impairments
core  

Unmet environmental needs and unmet healthcare needs in a population of young adults with cerebral palsy: what the SPARCLE study tells us

Frontiers in Rehabilitation Sciences
IntroductionOptimizing care for young adults with cerebral palsy is crucial for their physical and psychological well-being. The inadequacy of proximal environment may play a role in the provision of health services.
Jonathan Rioual, Célia Perret, Catherine Arnaud, Catherine Arnaud, Nicolas Vidart d’Egurbide Bagazgoïtia   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A Sleep Questionnaire for Children with Severe Psychomotor Impairment (SNAKE)—Concordance with a Global Rating of Sleep Quality

Children, 2018
Sleep problems are a common and serious issue in children with life-limiting conditions (LLCs) and severe psychomotor impairment (SPMI). The “Sleep Questionnaire for Children with Severe Psychomotor Impairment” (Schlaffragebogen für Kinder mit ...
Larissa Alice Dreier, Boris Zernikow, Markus Blankenburg, Julia Wager   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Practitioner review: Short-term and working memory impairments in neurodevelopmental disorders: diagnosis and remedial support [PDF]

, 2006
Background: This article provides an introduction to current models of working and short-term memory, their links with learning, and diagnosis of impairments. The memory impairments associated with a range of neurodevelopmental disorders (Down’s syndrome,
Gathercole, Susan Elizabeth, Alloway, T.P., Alloway, Tracy Packiam, Susan E. Gathercole, Gathercole, S.E., Tracy Packiam Alloway   +5 more
core   +1 more source

Is there an association between traumatic peripheral lesions and cognitive impairments in adults? A scoping review

, 2023
The aim of this scoping review was to critically review and synthesize the evidence concerning the relationship between traumatic peripheral lesions and cognitive impairments.
Zoghi, Maryam, Xue Zhang, Tianyi Li, Tamara Tse, Zhang, Xue, Li, Tianyi, Maryam Zoghi, Tse, Tamara   +7 more
core   +1 more source

Going Concern Risk and Bankruptcy Outcomes Associated with Property, Plant, and Equipment Intensity, Impairment, and Age

Risks
Corporate management and their auditors are required to evaluate whether there is a risk that the company’s ability to continue as a going concern is impaired.
Donald Ray Deis, J. Kenneth Reynolds, Christopher Wertheim, Tian Xu, Daqun Zhang   +4 more
doaj   +1 more source

The Convention for the Rights of Persons with Disabilities and Article 12: Prospective Feminist Lessons against the “Will and Preferences” Paradigm

Laws, 2015
Human rights have recently impacted on current conceptualisations of the rights and obligations owed to individuals with impairments, culminating in the UN Convention for the Rights of Persons with Disabilities.
Camillia Kong
doaj   +1 more source