Results 91 to 100 of about 575,905 (318)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Features of vertical stability of junior school children with visual impairments [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
The importance of vertical stability in the formation of the spatial organization of the body and correct posture for junior school children with visual impairments was determined.
Yurchenko A. A.
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Age related cognitive impairments and assistive web-base technology [PDF]

open access: yes, 2008
Several researchers argue that age related cognitive impairments have detrimental affect on use of web services by older adults. However little and systematic applied research has been conducted on how age related cognitive impairments might affect the ...
Money, A, Lines, L, Elliman, T
core  

Racial and ethnic differences in older adults’ willingness to be contacted about Alzheimer's disease research participation

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2020
Introduction We sought to examine the association of race/ethnicity with willingness to engage in studies that involve procedures typical of Alzheimer's disease (AD) clinical trials and determine whether any observed differences could be explained by ...
Christian R. Salazar   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Factor structure of the barriers to physical activity scale for youth with visual impairments

open access: yes, 2021
Youth with visual impairments (VIs) often experience unique barriers to physical activity compared with their sighted peers. A psychometrically sound scale for assessing barriers to physical activity for youth with VI is needed to facilitate research ...
Armstrong, Ellen   +5 more
core   +1 more source

Multiple Long-Term Conditions and Disability are Independently Associated with Higher Risk of Fall Among Community Adults: a Cross-Sectional Study

open access: yesRisk Management and Healthcare Policy
Aqeel M Alenazi,1 Norah A Alhwoaimel,1 Bader A Alqahtani,1 Mohammed M Alshehri,2 Ahmed S Alhowimel,1 Kamlesh Khunti,3 Mohammed S Alghamdi4 1Department of Health and Rehabilitation Sciences, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia ...
Alenazi AM   +6 more
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Visual Speech Perception in Children With Language Learning Impairments

open access: yes, 2016
Purpose - The purpose of the study was to assess the ability of children with developmental language learning impairments (LLIs) to use visual speech cues from the talking face.
Snell, C.   +3 more
core   +1 more source

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