Results 81 to 90 of about 768,930 (284)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

DEVELOPMENT OF FORMS OF STRUCTURAL MATHEMATICAL MODELING IN DYNAMICS OF MECHANICAL OSCILLATION SYSTEMS: IMPEDANCE AND POSSIBLE VARIANTS OF APPROACH

Proceedings of the Mongolian Academy of Sciences, 2017
Offering method of transformation of mathematical models of oscillation systems based on using of structural schemes. Structural analogs of mathematical models used for creature of variants of transfer functions of initial mechanical systems.
S V Eliseev, V B Kashuba, S K Kargapoltsev, A V Nikolaev   +3 more
doaj   +1 more source

Zero-Point Fluctuations and the Quenching of the Persistent Current in Normal Metal Rings

, 1999
The ground state of a phase-coherent mesoscopic system is sensitive to its environment. We investigate the persistent current of a ring with a quantum dot which is capacitively coupled to an external circuit with a dissipative impedance.
A. J. Bray, A. J. Leggett, A. M. Tsvelick, A. O. Caldeira, D. S. Golubev, F. W. J. Hekking, G.-L. Ingold, I. L. Aleiner, M. Büttiker, M. Büttiker, M. Büttiker, Markus Büttiker, N. Andrei, P. Cedraschi, P. Mohanty, P. W. Anderson, Pascal Cedraschi, S. Chakravarty, U. Weiss, V. V. Ponomarenko, Vadim V. Ponomarenko   +20 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Electromechanical coupling in polaronic ceria

JPhys Energy
Oxygen-defective metal oxides like cerium oxides exhibit giant electrostriction and field-induced piezoelectricity due to a dynamic electrosteric interplay between oxygen defects, ${\text{V}}_{\text{O}}^{ \cdot \cdot }$ , and the fluorite lattice.
Victor Buratto Tinti, Milica Vasiljevic, Mathias Grønborg, Huaiyu Chen, Valdemar Frederiksen, Innokenty Kantor, Jesper Wallentin, Henrik Bruus, Vincenzo Esposito   +8 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Numerical Simulation Study on the Impedance of the Communication Port of Liquid Launch Vehicle Gas-Filled Accumulators

Applied Sciences
To prevent pogo oscillation in liquid launch vehicles, it is essential to install a gas-filled accumulator near the pump with minimum flow inertance and a target-design level of flow resistance, which are the real and imaginary parts of communication ...
Tong Shi, Guozhu Liang, Yunqin He
doaj   +1 more source

Identifying rate limitation and a guide to design of fast‐charging Li‐ion battery

InfoMat, 2020
Fast‐charging is highly demanded for applications requiring short charging time. However, fast‐charging triggers serious problems, leading to decline in charge acceptance and energy efficiency, accelerated capacity degradation, and safety risk.
Sheng S. Zhang
doaj   +1 more source

LED receiver impedance and its effects on LED-LED visible light communications

, 2017
This paper experimentally demonstrates that the AC impedance spectrum of the LED as a photodetector heavily depends on the received optical power, which may cause the impedance mismatch between the LED and the post trans-impedance amplifier.
Huang, Boyang, Li, Shangbin, Xu, Zhengyuan   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source