Results 151 to 160 of about 1,600 (181)

Whole blood impedance aggregometry detects heparin-induced thrombocytopenia antibodies

Thrombosis Research, 2010
Heparin-induced thrombocytopenia (HIT) is a serious complication of heparin use. IgG antibodies to complexes of platelet factor 4 (PF4) and heparin trigger the clinical manifestations of HIT. Only a subset of these antibodies will activate platelets and these can only be identified with platelet aggregation (functional) assays. Heparin-induced platelet
Marie-Christine, Morel-Kopp, Margaret, Aboud, Chee Wee, Tan, Chandima, Kulathilake, Christopher, Ward   +4 more
openaire   +2 more sources

Decrease of Aggregation By Platelet Impedance Aggregometry ( MULTIPLATE ) in Patients Treated with Dabigatran

Blood, 2016
Abstract Introduction: Dabigatran is a direct oral anticoagulant (DOAC) that has been proved effective and safe in preventing thromboembolic events experienced by patients with non-valvular atrial fibrillation (AF). This drug acts directly inhibiting thrombin and particularly affects the intrinsic and the final coagulation pathways ...
Valentin Cabañas, Juan Jose Cerezo-Manchado, Faustino Garcia-Candel, Eduardo Salido, Raul Lopez-Perez, Ana Garcia-Hernandez, Merecedes Berenguer, Francesca Labbadia, Miguel Blanquer Blanquer, Jose Maria Moraleda   +9 more
openaire   +1 more source

Point-of-Care Whole Blood Impedance Aggregometry Versus Classical Light Transmission Aggregometry for Detecting Aspirin and Clopidogrel: The Results of a Pilot Study

Anesthesia & Analgesia, 2008
We determined whether whole blood impedance aggregometry using the Multiplate detects the effects of antiplatelet drugs as reliably as does classical light transmission aggregometry (LTA) or the platelet function analyzer PFA-100(R).Multiplate (M) assays, measuring changes in electrical resistance as aggregation units over time (AU*min), and LTA assays
Corinna, Velik-Salchner, Stephan, Maier, Petra, Innerhofer, Werner, Streif, Anton, Klingler, Christian, Kolbitsch, Dietmar, Fries   +6 more
openaire   +2 more sources

Effect of lactic acid addition to equine whole blood on platelet aggregation measured by impedance aggregometry

Veterinary Clinical Pathology, 2022
AbstractBackgroundAcidemia in sick or injured horses is often due to lactic acid accumulation. Alterations in platelet function and hemostasis are among numerous deleterious effects caused by decreased physiologic pH.ObjectivesWe aimed to evaluate the effect of hyperlactatemia and resultant acidemia on platelet aggregation in equine whole blood using ...
Christopher J. Lanier, Jennifer S. Taintor, Peter W. Christopherson, Elizabeth A. Spangler   +3 more
openaire   +2 more sources

The effect of adding lactic acid to canine whole blood on platelet aggregation as measured by impedance aggregometry

Veterinary Clinical Pathology, 2020
AbstractBackgroundAcidemia in sick dogs often results from the accumulation of lactic acid. The resulting decrease in blood pH can have many physiologic effects, including alteration of platelet function.ObjectivesWe aimed to evaluate the effect of hyperlactatemia and subsequent acidemia on platelet aggregation in canine blood using impedance ...
Cheryl A. Lawson, Elizabeth A. Spangler
openaire   +2 more sources

Multiplate whole blood impedance aggregometry: a new tool for von Willebrand disease

Journal of Thrombosis and Haemostasis, 2011
The diagnosis and characterization of von Willebrand disease (VWD) is a well-known challenge. Besides the clinical bleeding tendency, its diagnosis and subtyping require laboratory data, including measurement of PFA-100 closure time (CT), factor VIII:C, von Willebrand factor (VWF) antigen (VWF:Ag), VWF ristocetin cofactor activity (VWF:RCo), and ...
V. VALARCHE, C. DESCONCLOIS, T. BOUTEKEDJIRET, M. DREYFUS, V. PROULLE   +4 more
openaire   +1 more source

Variability of tissue factor‐activated thromboelastography and whole blood impedance platelet aggregometry in healthy dogs

Journal of Veterinary Emergency and Critical Care, 2018
AbstractObjectiveTo assess interindividual (CVG) and intraindividual (CVI) variability over time for results of thromboelastography (TEG) and whole‐blood impedance platelet aggregometry in healthy dogs.AnimalsSix healthy Beagle dogs.Measurements and Main ResultsTissue factor (TF)‐activated TEG and adenosine diphosphate (ADP) and arachidonic acid (AA ...
Sarah B, Shropshire, Christine S, Olver, Michael R, Lappin   +2 more
openaire   +2 more sources

Detection of small inhibitory effects of acetylsalicylic acid (ASA) by platelet impedance aggregometry in whole blood

Thrombosis Research, 1988
Our investigations have demonstrated on 10 volunteers receiving either 500 mg or 100 mg acetylsalicylic acid (ASA) that a low collagen concentration (1 microgram/ml) can best detect the aggregation defect caused by ASA. With the impedance aggregometry the mean inhibition reaches 82% and 52% with 500 mg and 100 mg ASA, respectively.
Sathiropas P, Marbet GA, Sahaphong S, Duckert F   +3 more
openaire   +3 more sources

AS-219: Comparison of Two Assays in Platelet Aggregometry: Whole Blood Impedance Platelet Aggregometry and Turbidimetric Platelet Aggregometry

The American Journal of Cardiology, 2010
Ruiqin Xie, Wei Cui, Hongbo Zhang, Fan Liu, Jing Liu, Xiaohong Yang   +5 more
openaire   +1 more source

Multiplate whole blood impedance aggregometry: A recent experience

Thrombosis and Haemostasis, 2008
Breugelmans, Jaime, Vertessen, Francine, Mertens, Gerhard, Gadisseur, Alain, van der Planken, Marc   +4 more
openaire   +2 more sources