Results 131 to 140 of about 22,474,821 (353)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Thermal correction to the Casimir force, radiative heat transfer, and an experiment
The low-temperature asymptotic expressions for the Casimir interaction between two real metals described by Leontovich surface impedance are obtained in the framework of thermal quantum field theory.
A. Lambrecht +90 more
core +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Research on current-mode damping impedance interface model based on adaptive impedance matching
With the development and progress of new energy electricity generation technology, a detailed study and test is required on new energy power generation equipment and micro-network system.
Liu Keyan +6 more
doaj +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Grid-forming converters controlled by virtual synchronous generator (VSG) provide a certain amount of inertia and damping support for new energy sources to be connected to the grid.
Wei LI, Meiling MA, Weiqing SUN
doaj +1 more source
Experimental validation of a two-dimensional shear-flow model for determining acoustic impedance [PDF]
Tests were conducted to validate a two-dimensional shear-flow analytical model for determining the acoustic impedance of a liner test specimen in a grazing-incidence, grazing-flow environment.
Jones, Michael G. +2 more
core +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Measuring the electrical impedance of mouse brain tissue [PDF]
We report on an experimental method to measure conductivity of cortical tissue. We use a pair of 5mm diameter Ag/AgCl electrodes in a Perspex sandwich device that can be brought to a distance of 400 microns apart.
Elbohouty, Maher +5 more
core +1 more source

