Results 61 to 70 of about 55,013 (262)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A neural network design for black-box identification of converter impedance models in arbitrary operating conditions

open access: yes电力工程技术
The impedance-based method is favored by engineering because it can analyze system stability under conditions with the unknown device control structure or parameters.
CHEN Bing   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Flexible Wideband Microstrip-Slotline-Microstrip Power Divider and its Application to Antenna Array

open access: yesIEEE Access, 2019
In the satellite microwave power transmission (MPT) system, antenna arrays are usually adopted for a higher gain. For the passive wideband antenna array, wideband power dividers are essential when the feed network is constructed.
Bing Xiao   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

An AI-based neural network approach for real-time monitoring of water management related PEM fuel cells degradation

open access: yesEnergy Conversion and Management: X
In this study, the evaluation and classification of fuel cell degradation mechanisms are addressed by using impedance data. The focus is on water management related degradation trends that affect the healthy performance of polymer electrolyte membrane ...
Oliver Schopen   +3 more
doaj   +1 more source

Integrated Full-Frequency Impedance Modeling and Stability Analysis of the Train-Network Power Supply System for High-Speed Railways

open access: yesEnergies, 2018
To investigate the harmonic resonance, harmonic instability and low-frequency oscillation phenomena in high-speed railways, this paper proposes a full-frequency impedance model of the train-traction network system (simplified as ‘train-network ...
Xinyu Zhang   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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