Results 71 to 80 of about 55,013 (262)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A Dynamic Impedance Matching Method and Frequency Tracking of Piezoelectric Transducers [PDF]
Zhengzhou Daxue xuebao. Gongxue banDynamic impedance matching technology can improve the output power and energy conversion efficiency of piezoelectric transducers. Most of the existing dynamic impedance matching method was intelligent numerical optimization algorithm, but the intelligent
JI Yuebo +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Gong-kuang zidonghua, 2019 In view of the problem that the input impedance does not match the RF internal resistance and the output power decreases due to the change of transmission distance or load in magnetic resonant coupling wireless power transmission system, an impedance ...
YUAN Shiqiang +4 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
A Dual-Path Neural Network for High-Impedance Fault Detection
MathematicsHigh-impedance fault detection poses significant challenges for distribution network maintenance and operation. We propose a dual-path neural network for high-impedance fault detection.
Keqing Ning +6 more
doaj +1 more source
IMPEDANCE IMAGE RECONSTRUCTION WITH ARTIFICIAL NEURAL NETWORK IN ELECTRICAL IMPEDANCE TOMOGRAPHY
European Journal of Technic, 2019 Electrical impedance tomography views the electrical properties of the objects by injecting current with surface electrodes and measuring voltages. Then using a reconstructing algorithm, from the measured voltage-current values, conductivity distribution of the object calculated.
openaire +4 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
机车电传动, 2017 The low-frequency oscillation phenomenon had been frequently occurred in China electrified railways, which caused the traction locked of the train and the protection tripped of power supply system as well as other accidents.
TAO Yan
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