Results 41 to 50 of about 3,866 (181)

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source

Issues Determining Direct Airways Hyperresponsiveness in Mice

Frontiers in Physiology, 2012
Airways hyperresponsiveness (AHR) is frequently a primary outcome in mouse models of asthma. There are, however, a number of variables that may affect the outcome of such measurements and the interpretation of the results.
Lennart Karl, Alf Lundblad
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonist‐Based Agents and Body Composition: Filling More Gaps

Obesity, EarlyView.
ABSTRACT The last 2 decades have seen historic advances in the treatment of obesity. We are entering an era of defining obesity not by weight‐based outcomes but by changes in body composition. Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are forming the platform for obesity treatments based on their high level of efficacy. Body composition can
Robert L. Dubin, Tierra N. Sanders, Hunter M. Schwab, Steven B. Heymsfield, Frank L. Greenway   +4 more
wiley   +1 more source

Nasal Airway Transcriptome Reflects Selected Asthma‐Associated Gene Signatures in the Lower Airways

Allergy, EarlyView.
Seven genes and two gene modules were consistently associated with asthma in both airway compartments in ARMS and were validated in ATLANTIS. The two modules reflected IL‐13 related inflammation and mast cell activity, respectively. Nasal gene signatures provide a non‐invasive proxy for selected bronchial asthma‐associated gene signatures. ARMS, Asthma
Hui Wen, Tessa Kole, Orestes A. Carpaij, Tatiana Karp, Victor Guryev, Alen Faiz, Kian Fan Chung, Pankaj Bhavsar, Ian M. Adcock, Salman Siddiqui, Andy Lan, Katie L. Raby, Nazanin Zounemat‐Kermani, Chris Brightling, Dave Singh, Janwillem Kocks, Monica Kraft, Bianca Beghé, Klaus F. Rabe, Alberto Papi, Machteld N. Hylkema, Martijn C. Nawijn, Maarten van den Berge   +22 more
wiley   +1 more source

Therapeutic targeting of bleomycin‐induced pulmonary fibrosis by human bone marrow mesenchymal stem cell‐derived extracellular vesicles and/or pirfenidone: Impact of sex in mature adult mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell‐derived extracellular vesicles (BM‐MSC‐EVs) with an IPF treatment, pirfenidone (PFD), in mature adult mice with established pulmonary ...
Jennie S. Charoenphannathon, Simon G. Royce, Yasmin Higham, Jane E. Bourke, Chrishan S. Samuel   +4 more
wiley   +1 more source

Design and implementation of a portable impedance cardiography system for noninvasive stroke volume monitoring

Journal of Medical Signals and Sensors, 2016
Measurement of the stroke volume (SV) and its changes over time can be very helpful for diagnosis of dysfunctions in the blood circulatory system and monitoring their treatments.
Hassan Yazdanian, Amin Mahnam, Mehdi Edrisi, Morteza Abdar Esfahani   +3 more
doaj  

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn, Alexandra Riddell, Ashton Bernard, Jennifer Haggarty, Stefan Weidt, Jawza Alenazi, Erika Trabold, Delyth Graham, Laura B. Dowsett, James Leiper, Alyson A. Miller   +10 more
wiley   +1 more source

Short Distance Impedance Pneumography

Current Directions in Biomedical Engineering, 2018
Gold-standards for biosignal acquisition require body-spanning sensor positioning which is contradictory to the high integration of modern wearable medical monitors.
Klum Michael, Schenck Tianhao, Pielmus Alexandru, Tigges Timo, Orglmeister Reinhold   +4 more
doaj   +1 more source

Impulse oscillometry in the diagnosis of obstructive ventilation disorders in pulmonary tuberculosis patients

Туберкулез и болезни лёгких, 2019
Impulse oscillometry (IO) possesses certain advantages (being non-invasive and requiring no special breathing maneuvers) but fundamental differences from the well-known methods of external respiration function assessment make it difficult to introduce it
L. D. Kiryukhina, O. S. Volodich, N. V. Denisova, N. G. Nefedova, S. A. Kovaleva, L. I. Аrchakova   +5 more
doaj   +1 more source

Feasibility and usability of three consecutive nights with self‐applied, home polysomnography

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary In‐laboratory polysomnography, the gold‐standard for diagnosing sleep disorders, is resource‐demanding and not conducive to multiple night evaluations. Ambulatory polysomnography, especially when self‐applied, could be a viable alternative. This study aimed to assess the feasibility and reliability of self‐applied polysomnography over three ...
Dimitri Ferretti, Anna S. Islind, Kristín A. Ólafsdóttir, Sigridur Sigurdardottir, Kamilla R. Jóhannsdóttir, Jan Hedner, Ludger Grote, Erna Sif Arnardottir   +7 more
wiley   +1 more source