Results 91 to 100 of about 109,970 (304)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Ultra-thin low frequency perfect sound absorber with high ratio of active area [PDF]

, 2018
A concept of ultra-thin low frequency perfect sound absorber is proposed and demonstrated experimentally. To minimize non-linear effects, an high ratio of active area to total area is used to avoid large localized amplitudes.
Aurégan, Yves
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

The Influence of Conventional Earmuff Sound Absorbers on Psychoacoustic Factors: A Laboratory Study

International Journal of Environmental Health Engineering
Aim: Traditional indicators used for evaluating hearing protectors do not capture their impact on psychoacoustic parameters. Therefore, this study aimed to analyze commonly used absorbers in earmuffs and their influence on psychoacoustic indicators ...
Mahshid Khaki, Hadi Asady, Siamak Pourabdian, Samane Khorshidikia, Farhad Forouharmajd   +4 more
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Acoustic Absorption of Mortar Composites with Waste Material

Archives of Acoustics, 2013
This paper presents an investigation about acoustic absorption of mortars with partial replacement of sand by waste (plywood formwork, rice husk, and thermoplastic shoe counters), examining different levels of replacement (0%, 5%, 10%, 25%, and 50%). The
Marco Aurelio STUMPF, Fernanda FLACH, Josiane RESCHKE PIRES, Marlova PIVA KULAKOWSKI   +3 more
doaj  

Application of acoustically tuned resonators for the improvement of sound insulation in aircraft [PDF]

, 2005
One of the aims of the EU project FACE (Friendly Aircraft Cabin Environment) is to reduce aircraft interior noise. For modern aircraft flying at cruise conditions, the turbulent boundary layer is the main source for cabin noise.
Boer, A. de, Hannink, M.H.C., Vlasma, J.P., Wijnant, Y.H.   +3 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Utilizing Waste Cotton/Pigeon Pea Stalk Fibers Composites for Enhanced Sound Absorption and Insulation in Automotive Interiors

Journal of Natural Fibers
This study investigates the synthesis and characterization of composite materials, pigeon pea stem, and cotton fibers blended in different ratios such as 100/0, 70/30, 60/40, 50/50, 30/70, and 0/100.
Ariharasudhan Subramanian, Senthil Kumar Selvaraj, Rajaram Mani, Preethibha Chandrasekaran, Shanthi Kunjuraman, Ramratan Guru, Sakthivel Santhanam   +6 more
doaj   +1 more source