Results 61 to 70 of about 1,368,893 (306)

Propagation of Shear Horizontal Wave at Magneto-Electro-Elastic Structure Subjected to Mechanically Imperfect Interface [PDF]

Mechanics of Advanced Composite Structures
This study delves into the investigation of shear horizontal transverse waves within a structure composed of a layer and a semi-infinite medium. The layer considered in this work is made of functionally graded magneto-electro-elastic material, and the ...
Anandakrishnan Akshaya, Santosh Kumar, Kulandhaivel Hemalatha   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

FEM-BEM modeling of dynamic responses of saturated soil around fluid-filled lined tunnel with imperfect soil-lining interface under water hammer

Yantu gongcheng xuebao
This study employs the Finite Element Method-Boundary Element Method (FEM-BEM) to simulate the dynamic response of saturated soil around a fluid-filled circular tunnel under water hammer loading, accounting for imperfect bonding at the soil-lining ...
FU Yiming 1, HUANG Chao 3, QIAN Jiangu 1, 2
doaj   +1 more source

Thermo-mechanical Loading of Laminates with Imperfect Interfaces

Procedia Engineering, 2014
AbstractComposite laminates are currently being pursued for structures which may be subjected to explosive threats in aggressive environments, characterized by extreme temperatures and seawater. A mechanical model is formulated for laminated plates subjected to thermo-mechanical loading and deforming in cylindrical bending; the layers are assumed to be
MASSABO', ROBERTA, CAMPI, FRANCESCA
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

On the Thermoelectric Effect of Interface Imperfections

, 1999
Ordinary thermocouples use the well-known Seebeck effect to measure the temperature at the junction of two different conductors. The electromotive force generated by the heat depends on the difference between the respective thermoelectric powers of the contacting metals and the junction temperature.
Hu, Jiangtao, Nagy, Peter
openaire   +3 more sources

Imperfect-Recall Abstractions with Bounds

, 2018
We develop the first general, algorithm-agnostic, solution quality guarantees for Nash equilibria and approximate self-trembling equilibria computed in imperfect-recall abstractions, when implemented in the original (perfect-recall) game. Our results are
Christian Kroer (5415797), Tuomas W Sandholm (5409227)   +1 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Protein docking prediction using predicted protein-protein interface

BMC Bioinformatics, 2012
Background Many important cellular processes are carried out by protein complexes. To provide physical pictures of interacting proteins, many computational protein-protein prediction methods have been developed in the past. However, it is still difficult
Li Bin, Kihara Daisuke
doaj   +1 more source

A Genome-Wide Survey of the Microsatellite Content of the Globe Artichoke Genome and the Development of a Web-Based Database. [PDF]

PLoS ONE, 2016
The recently acquired genome sequence of globe artichoke (Cynara cardunculus var. scolymus) has been used to catalog the genome's content of simple sequence repeat (SSR) markers.
Ezio Portis, Flavio Portis, Luisa Valente, Andrea Moglia, Lorenzo Barchi, Sergio Lanteri, Alberto Acquadro   +6 more
doaj   +1 more source