Results 121 to 130 of about 733,404 (291)

On application of an imperfect repair model in maintenance scheduling

, 2015
International audienceThe paper studies the failure dataset from a fleet of six load-haul-dump machines in a Swedish mine. The data consists of time between successive failures of each machine during a period of two years.
Dijoux, Yann, Fouladirad, Mitra, Tuan Nguyen, Mitra Fouladirad, Nguyen, Tuan, Yann Dijoux   +5 more
core   +1 more source

Functional Nanostructured Lipid Carrier-Enriched Hydrogels Tailored to Repair Damaged Epidermal Barrier

Gels
In this study, a functional nanostructured lipid carriers (NLCs)-based hydrogel was developed to repair the damaged epidermal skin barrier. NLCs were prepared via a high-energy approach, using argan oil and beeswax as liquid and solid lipids ...
Radwan Joukhadar, Laura Nižić Nodilo, Jasmina Lovrić, Anita Hafner, Ivan Pepić, Mario Jug   +5 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Imperfect Monitoring and Impermanent Reputations [PDF]

We study the long-run sustainability of reputations in games with imperfect public monitoring. It is impossible to maintain a permanent reputation for playing a strategy that does not play an equilibrium of the game without uncertainty about types. Thus,
George J. Mailath, Larry Samuelson, Martin W. Cripps   +2 more
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Proportional Intensity Model considering imperfect repair for repairable systems

, 2013
The Proportional Intensity Model (PIM) extends the classical Proportional Hazard Model (PHM) in order to deal with repairable systems. This paper develops a more general PIM model which uses the imperfect model as baseline function.
Kumar, Uday, Fuqing, Yuan, Kumar, Uday,, Fuqing, Yuan,   +3 more
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Discrete imperfect repair.

, 1992
A discrete imperfect repair model is studied, it consists of units that try to perform jobs dynamically in time and that at failure may be repaired and are allowed to try to do again the jobs in which they failed until either eventual completions of the ...
Rocha-Martinez, Jose Maria.
core   +2 more sources

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

System Reliability of Controllable Repair System With Multiple Imperfect Coverage

, 2014
[[abstract]]This paper investigated the reliability characteristics of a controllable repair system with multiple imperfect coverage. The time-to-failure and the time-to-repair of the active and standby units are assumed to be exponentially distributed ...
Kuo-Hsiung, W;Wang, Kuo-Hsiung;Li, Yen-Chen;Li, Yen-Chen;許昌賢;Hsu, Chang-Hsien
core